Cross-sectional investigation of pneumococcal vaccination patterns in HIV patients at a tertiary care hospital in Riyadh, Saudi Arabia
Background: People living with HIV (PLWH) are recognized as a high-risk population for opportunistic infections, including community-acquired pneumonia (CAP). Therefore, the United States Centers for Disease Control and Prevention (US-CDC) and Saudi Ministry of health (MOH) advocate for pneumococcal...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-07-01
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| Series: | Journal of Infection and Public Health |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1876034125001327 |
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| author | Reem Binsuwaidan Enas Mosaffer Alghamdi Ethar Abdullhameed Otaif Maram Saud ALqutaym Yahya Ali Mohzari Ahmed Ali Alrashed Rowdan Zeyan Alderaan Ahmed Ajlan Alsheheri Alaa Alhubaishi Lina I Alnajjar |
| author_facet | Reem Binsuwaidan Enas Mosaffer Alghamdi Ethar Abdullhameed Otaif Maram Saud ALqutaym Yahya Ali Mohzari Ahmed Ali Alrashed Rowdan Zeyan Alderaan Ahmed Ajlan Alsheheri Alaa Alhubaishi Lina I Alnajjar |
| author_sort | Reem Binsuwaidan |
| collection | DOAJ |
| description | Background: People living with HIV (PLWH) are recognized as a high-risk population for opportunistic infections, including community-acquired pneumonia (CAP). Therefore, the United States Centers for Disease Control and Prevention (US-CDC) and Saudi Ministry of health (MOH) advocate for pneumococcal vaccination among all PLWH as a crucial preventive measure against pneumococcal infections. Hence, this study aims to investigate the prescribing patterns of pneumococcal vaccines for PLWH at a tertiary care hospital. As PCV15 and PCV20 were not available until 2022, this study focuses on the prescribing patterns of PCV13 and PPSV23. Methods: This cross-sectional study was conducted to assess the prescribing patterns of pneumococcal vaccines among PLWH attending the HIV clinic at a tertiary hospital in Riyadh, Saudi Arabia. Utilizing medical records from PLWH who visited the HIV clinic between January 1987 and December 2022, demographic data, clinical characteristics, antiretroviral therapy details, and pneumococcal vaccination records were collected. Statistical analyses were performed using the Statistical Package for Social Sciences (SPSS) version 21 (SPSS Inc., Armonk, New York, USA). Results: Of the 346 identified patients, the majority (81 %) were male, with a median age of 45 years. A significant proportion had not received any pneumococcal vaccinations (98.6 %), while only 2 patients (0.56 %) completed the full series of pneumococcal vaccines (PCV13-PPSV23), and 3 patients (0.84 %) received a single dose of PCV13. Nearly all patients (99 %) reported regular attendance at the HIV clinic, with the vast majority (98.3 %) receiving antiretroviral therapy (ART). Conclusion: This study revealed a notable deficiency in pneumococcal vaccine coverage among PLWH. Therefore, additional measures are imperative to improve pneumococcal vaccine uptake and reduce the risk of invasive pneumococcal diseases within this vulnerable population. |
| format | Article |
| id | doaj-art-5e6b605fe3974ee6bb236e2016716a02 |
| institution | DOAJ |
| issn | 1876-0341 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Infection and Public Health |
| spelling | doaj-art-5e6b605fe3974ee6bb236e2016716a022025-08-20T03:12:02ZengElsevierJournal of Infection and Public Health1876-03412025-07-0118710278310.1016/j.jiph.2025.102783Cross-sectional investigation of pneumococcal vaccination patterns in HIV patients at a tertiary care hospital in Riyadh, Saudi ArabiaReem Binsuwaidan0Enas Mosaffer Alghamdi1Ethar Abdullhameed Otaif2Maram Saud ALqutaym3Yahya Ali Mohzari4Ahmed Ali Alrashed5Rowdan Zeyan Alderaan6Ahmed Ajlan Alsheheri7Alaa Alhubaishi8Lina I Alnajjar9Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi ArabiaPharmD Graduate, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi ArabiaPharmD Graduate, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi ArabiaPharmD Graduate, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi ArabiaDepartment of Clinical Pharmacy, King Saud Medical City, Riyadh, Saudi ArabiaDepartment of Clinical Pharmacy, King Fahad Medical City, Riyadh, Saudi ArabiaDepartment of Infectious Diseases, King Saud Medical City, Riyadh, Saudi ArabiaDepartment of Infectious Diseases, King Saud Medical City, Riyadh, Saudi ArabiaDepartment of Pharmacy Practice, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi ArabiaDepartment of Pharmacy Practice, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia; Corresponding author.Background: People living with HIV (PLWH) are recognized as a high-risk population for opportunistic infections, including community-acquired pneumonia (CAP). Therefore, the United States Centers for Disease Control and Prevention (US-CDC) and Saudi Ministry of health (MOH) advocate for pneumococcal vaccination among all PLWH as a crucial preventive measure against pneumococcal infections. Hence, this study aims to investigate the prescribing patterns of pneumococcal vaccines for PLWH at a tertiary care hospital. As PCV15 and PCV20 were not available until 2022, this study focuses on the prescribing patterns of PCV13 and PPSV23. Methods: This cross-sectional study was conducted to assess the prescribing patterns of pneumococcal vaccines among PLWH attending the HIV clinic at a tertiary hospital in Riyadh, Saudi Arabia. Utilizing medical records from PLWH who visited the HIV clinic between January 1987 and December 2022, demographic data, clinical characteristics, antiretroviral therapy details, and pneumococcal vaccination records were collected. Statistical analyses were performed using the Statistical Package for Social Sciences (SPSS) version 21 (SPSS Inc., Armonk, New York, USA). Results: Of the 346 identified patients, the majority (81 %) were male, with a median age of 45 years. A significant proportion had not received any pneumococcal vaccinations (98.6 %), while only 2 patients (0.56 %) completed the full series of pneumococcal vaccines (PCV13-PPSV23), and 3 patients (0.84 %) received a single dose of PCV13. Nearly all patients (99 %) reported regular attendance at the HIV clinic, with the vast majority (98.3 %) receiving antiretroviral therapy (ART). Conclusion: This study revealed a notable deficiency in pneumococcal vaccine coverage among PLWH. Therefore, additional measures are imperative to improve pneumococcal vaccine uptake and reduce the risk of invasive pneumococcal diseases within this vulnerable population.http://www.sciencedirect.com/science/article/pii/S1876034125001327Pneumococcal vaccinePLWHHIVPrescribing patternCommunity acquired pneumoniaRiyadh |
| spellingShingle | Reem Binsuwaidan Enas Mosaffer Alghamdi Ethar Abdullhameed Otaif Maram Saud ALqutaym Yahya Ali Mohzari Ahmed Ali Alrashed Rowdan Zeyan Alderaan Ahmed Ajlan Alsheheri Alaa Alhubaishi Lina I Alnajjar Cross-sectional investigation of pneumococcal vaccination patterns in HIV patients at a tertiary care hospital in Riyadh, Saudi Arabia Journal of Infection and Public Health Pneumococcal vaccine PLWH HIV Prescribing pattern Community acquired pneumonia Riyadh |
| title | Cross-sectional investigation of pneumococcal vaccination patterns in HIV patients at a tertiary care hospital in Riyadh, Saudi Arabia |
| title_full | Cross-sectional investigation of pneumococcal vaccination patterns in HIV patients at a tertiary care hospital in Riyadh, Saudi Arabia |
| title_fullStr | Cross-sectional investigation of pneumococcal vaccination patterns in HIV patients at a tertiary care hospital in Riyadh, Saudi Arabia |
| title_full_unstemmed | Cross-sectional investigation of pneumococcal vaccination patterns in HIV patients at a tertiary care hospital in Riyadh, Saudi Arabia |
| title_short | Cross-sectional investigation of pneumococcal vaccination patterns in HIV patients at a tertiary care hospital in Riyadh, Saudi Arabia |
| title_sort | cross sectional investigation of pneumococcal vaccination patterns in hiv patients at a tertiary care hospital in riyadh saudi arabia |
| topic | Pneumococcal vaccine PLWH HIV Prescribing pattern Community acquired pneumonia Riyadh |
| url | http://www.sciencedirect.com/science/article/pii/S1876034125001327 |
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