The Importance of the Correlation between CCT and Corneal Curvature in Refractive Surgery
Background: The aim of this study was to analyze the relationship between central corneal thickness (CCT) and corneal curvature (CC) in patients with refractive anomalies and emmetropes, in three different age groups. Methods and Results: The study included 330 respondents, with a total of 660 eyes...
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International Medical Research and Development Corporation
2025-06-01
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| Online Access: | http://www.ijbm.org/articles/i58/ijbm_15(2)_oa5.pdf |
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| author | Mimoza Ismaili |
| author_facet | Mimoza Ismaili |
| author_sort | Mimoza Ismaili |
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| description | Background: The aim of this study was to analyze the relationship between central corneal thickness (CCT) and corneal curvature (CC) in patients with refractive anomalies and emmetropes, in three different age groups.
Methods and Results: The study included 330 respondents, with a total of 660 eyes, divided into two groups. The test group included 180 respondents with refractive anomalies (65 respondents with hypermetropia, 65 with myopia, and 50 with astigmatism); the control group included 150 emmetropic respondents with uncorrected visual acuity (VA) – 6/6 in both eyes. Corneal curvature was measured by automated keratometry. We analyzed mean CC (Km), also known as mean keratometry, which is the average of the two major meridians of CC (K1 and K2) measured in diopters (D). CCT was measured by ultrasonic pachymetry.
The mean CCT in the myopic group was 521.0±28.2 μm, which was lower than in both the control group (550.0±18.0 μm) and the astigmatic groups (530.3±30.0 μm). In the emmetropic group, with increasing age, the CCT values decreased from 557.6±19.7 μm in the age group <20 years to 549.5±15.7 μm in the age group 20–29 years and 545.5±4.0 μm in the age group ≥30 years (P<0.001). In the groups of patients with refractive abnormalities, we did not find a significant difference between the mean CCT values depending on the age of the patients (P>0.05). In the astigmatism and emmetropic groups, we found no statistically significant difference between the mean CCT values depending on gender (P>0.05). In the hypermetropic group, the mean CCT values were higher in women (569.1 ± 28.9 μm) than in men (555.1 ± 23.5 μm) (P=0.008). At the same time, in the myopic group, the CCT values were higher in men (529.5 ± 28.0 μm) than in women (516.0 ± 41.8 μm) (P=0.049). Regarding the correlation between CCT and CC, we found no significant correlation in the hypermetropic (rs=-0.101; P=0.249) and myopic (rs=-0.0101; P=0.869) groups. However, a statistically significant low negative correlation was found between CCT and Km in the astigmatism group (rs=-0.322; P=0.001), and a statistically significant low positive correlation was found between CCT and Km in the control group (rs=0.144; P=0.0120).
Conclusion: CCT is found to be thicker in hypermetropic patients than in emmetropes. With increasing age, the cornea tends to become thinner. We found no significant correlation between the CCT values and corneal keratometry. Also, we found that in the astigmatism group, the CCT values were higher in the corneal keratometric group 42-48D. The cornea is inclined to become thinner and steeper in myopes. These biometric findings will serve to update and advance protocols in refractory surgery. |
| format | Article |
| id | doaj-art-5e6244443cfb4539b138d831d7ce9cdb |
| institution | OA Journals |
| issn | 2158-0510 2158-0529 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | International Medical Research and Development Corporation |
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| series | International Journal of Biomedicine |
| spelling | doaj-art-5e6244443cfb4539b138d831d7ce9cdb2025-08-20T02:05:29ZengInternational Medical Research and Development CorporationInternational Journal of Biomedicine2158-05102158-05292025-06-0115229930410.21103/Article15(2)_OA5The Importance of the Correlation between CCT and Corneal Curvature in Refractive SurgeryMimoza Ismaili0Department of Ophthalmology, Faculty of Medicine, University of Pristina “Hasan Prishtina”, Prishtina, KosovoBackground: The aim of this study was to analyze the relationship between central corneal thickness (CCT) and corneal curvature (CC) in patients with refractive anomalies and emmetropes, in three different age groups. Methods and Results: The study included 330 respondents, with a total of 660 eyes, divided into two groups. The test group included 180 respondents with refractive anomalies (65 respondents with hypermetropia, 65 with myopia, and 50 with astigmatism); the control group included 150 emmetropic respondents with uncorrected visual acuity (VA) – 6/6 in both eyes. Corneal curvature was measured by automated keratometry. We analyzed mean CC (Km), also known as mean keratometry, which is the average of the two major meridians of CC (K1 and K2) measured in diopters (D). CCT was measured by ultrasonic pachymetry. The mean CCT in the myopic group was 521.0±28.2 μm, which was lower than in both the control group (550.0±18.0 μm) and the astigmatic groups (530.3±30.0 μm). In the emmetropic group, with increasing age, the CCT values decreased from 557.6±19.7 μm in the age group <20 years to 549.5±15.7 μm in the age group 20–29 years and 545.5±4.0 μm in the age group ≥30 years (P<0.001). In the groups of patients with refractive abnormalities, we did not find a significant difference between the mean CCT values depending on the age of the patients (P>0.05). In the astigmatism and emmetropic groups, we found no statistically significant difference between the mean CCT values depending on gender (P>0.05). In the hypermetropic group, the mean CCT values were higher in women (569.1 ± 28.9 μm) than in men (555.1 ± 23.5 μm) (P=0.008). At the same time, in the myopic group, the CCT values were higher in men (529.5 ± 28.0 μm) than in women (516.0 ± 41.8 μm) (P=0.049). Regarding the correlation between CCT and CC, we found no significant correlation in the hypermetropic (rs=-0.101; P=0.249) and myopic (rs=-0.0101; P=0.869) groups. However, a statistically significant low negative correlation was found between CCT and Km in the astigmatism group (rs=-0.322; P=0.001), and a statistically significant low positive correlation was found between CCT and Km in the control group (rs=0.144; P=0.0120). Conclusion: CCT is found to be thicker in hypermetropic patients than in emmetropes. With increasing age, the cornea tends to become thinner. We found no significant correlation between the CCT values and corneal keratometry. Also, we found that in the astigmatism group, the CCT values were higher in the corneal keratometric group 42-48D. The cornea is inclined to become thinner and steeper in myopes. These biometric findings will serve to update and advance protocols in refractory surgery.http://www.ijbm.org/articles/i58/ijbm_15(2)_oa5.pdfcentral corneal thicknesscorneal curvaturerefractive anomalies |
| spellingShingle | Mimoza Ismaili The Importance of the Correlation between CCT and Corneal Curvature in Refractive Surgery International Journal of Biomedicine central corneal thickness corneal curvature refractive anomalies |
| title | The Importance of the Correlation between CCT and Corneal Curvature in Refractive Surgery |
| title_full | The Importance of the Correlation between CCT and Corneal Curvature in Refractive Surgery |
| title_fullStr | The Importance of the Correlation between CCT and Corneal Curvature in Refractive Surgery |
| title_full_unstemmed | The Importance of the Correlation between CCT and Corneal Curvature in Refractive Surgery |
| title_short | The Importance of the Correlation between CCT and Corneal Curvature in Refractive Surgery |
| title_sort | importance of the correlation between cct and corneal curvature in refractive surgery |
| topic | central corneal thickness corneal curvature refractive anomalies |
| url | http://www.ijbm.org/articles/i58/ijbm_15(2)_oa5.pdf |
| work_keys_str_mv | AT mimozaismaili theimportanceofthecorrelationbetweencctandcornealcurvatureinrefractivesurgery AT mimozaismaili importanceofthecorrelationbetweencctandcornealcurvatureinrefractivesurgery |