A combination treatment of low-dose dexamethasone and aspirin-triggered resolvin D1 reduces Sjögren syndrome–like features in a mouse modelWhy Is This Important?

A combination treatment of low-dose dexamethasone and aspirin-triggered resolvin D1 reduces Sjögren syndrome–like features in a mouse modelWhy Is This Important?

Background: Sjögren syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltration and diminished secretory function of the salivary glands. Dexamethasone (DEX) resolves dry mouth and lymphocytic infiltration; however, this treatment is difficult to maintain because of multiple adv...

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Bibliographic Details
Main Authors: Harim Tavares dos Santos, DDS, PhD, Frank Maslow, BS, Kihoon Nam, PhD, Bryan Trump, DDS, Gary A. Weisman, PhD, Olga J. Baker, DDS, PhD
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:JADA Foundational Science
Subjects:
Salivary glands
inflammation
resolvins
steroids
lipid mediators
Online Access:http://www.sciencedirect.com/science/article/pii/S2772414X22000123
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