Birch reductive arylation by mechanochemical anionic activation of polycyclic aromatic compounds
Abstract Birch reduction is a well-known process for transforming aromatic compounds. The reduction of aromatic rings using alkali metals produces anionic species that react with protons or electrophiles. Generally, this reaction is accompanied by significant limitations in the available nucleophile...
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| Main Authors: | Yoshifumi Toyama, Akiko Yagi, Kenichiro Itami, Hideto Ito |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-60318-y |
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