Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure?
There is an increasing awareness of the prevalence of iron deficiency in patients with heart failure (HF), and its contributory role in the morbidity and mortality of HF. Iron is a trace element necessary for cells due to its capacity to transport oxygen and electrons. The prevalence of iron deficie...
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| Format: | Article |
| Language: | English |
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Radcliffe Medical Media
2019-11-01
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| Series: | Cardiac Failure Review |
| Online Access: | https://www.cfrjournal.com/articles/Iron-Deficiency-Comorbidity-Heart-Failure |
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| _version_ | 1850110714228768768 |
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| author | Nicole Ebner Stephan von Haehling |
| author_facet | Nicole Ebner Stephan von Haehling |
| author_sort | Nicole Ebner |
| collection | DOAJ |
| description | There is an increasing awareness of the prevalence of iron deficiency in patients with heart failure (HF), and its contributory role in the morbidity and mortality of HF. Iron is a trace element necessary for cells due to its capacity to transport oxygen and electrons. The prevalence of iron deficiency increases with the severity of HF. For a long time the influence of iron deficiency was underestimated, especially in terms of worsening of cardiovascular diseases and developing anaemia. In recent years, studies with intravenous iron agents in patients with iron deficiency and HF showed new insights into the improvement of iron therapy. Additionally, experimental studies supporting the understanding of iron metabolism and the resulting pathophysiological pathways of iron have been carried out. The aim of this mini review is to highlight why iron deficiency is recognised as an important comorbidity in HF. |
| format | Article |
| id | doaj-art-5e4dfbc6c9514990b371af8aa2c59614 |
| institution | OA Journals |
| issn | 2057-7540 2057-7559 |
| language | English |
| publishDate | 2019-11-01 |
| publisher | Radcliffe Medical Media |
| record_format | Article |
| series | Cardiac Failure Review |
| spelling | doaj-art-5e4dfbc6c9514990b371af8aa2c596142025-08-20T02:37:46ZengRadcliffe Medical MediaCardiac Failure Review2057-75402057-75592019-11-015317317510.15420/cfr.2019.9.2Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure?Nicole Ebner0Stephan von Haehling1Department of Cardiology and Pneumology, University Medical Centre Goettingen, Goettingen, GermanyDepartment of Cardiology and Pneumology, University Medical Centre Goettingen, Goettingen, GermanyThere is an increasing awareness of the prevalence of iron deficiency in patients with heart failure (HF), and its contributory role in the morbidity and mortality of HF. Iron is a trace element necessary for cells due to its capacity to transport oxygen and electrons. The prevalence of iron deficiency increases with the severity of HF. For a long time the influence of iron deficiency was underestimated, especially in terms of worsening of cardiovascular diseases and developing anaemia. In recent years, studies with intravenous iron agents in patients with iron deficiency and HF showed new insights into the improvement of iron therapy. Additionally, experimental studies supporting the understanding of iron metabolism and the resulting pathophysiological pathways of iron have been carried out. The aim of this mini review is to highlight why iron deficiency is recognised as an important comorbidity in HF.https://www.cfrjournal.com/articles/Iron-Deficiency-Comorbidity-Heart-Failure |
| spellingShingle | Nicole Ebner Stephan von Haehling Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure? Cardiac Failure Review |
| title | Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure? |
| title_full | Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure? |
| title_fullStr | Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure? |
| title_full_unstemmed | Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure? |
| title_short | Why is Iron Deficiency Recognised as an Important Comorbidity in Heart Failure? |
| title_sort | why is iron deficiency recognised as an important comorbidity in heart failure |
| url | https://www.cfrjournal.com/articles/Iron-Deficiency-Comorbidity-Heart-Failure |
| work_keys_str_mv | AT nicoleebner whyisirondeficiencyrecognisedasanimportantcomorbidityinheartfailure AT stephanvonhaehling whyisirondeficiencyrecognisedasanimportantcomorbidityinheartfailure |