Review of Interventional Therapies for Refractory Pediatric Migraine

This is a review of the latest and seminal evidence in pediatric migraine. It covers the etiology and pathophysiology known today, and then will review treatment options, efficacy and safety, quality of data and indications. Though migraine is usually regarded as an infliction in adults, it is not u...

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Main Authors: Jacquelin Peck, Justin Zeien, Megha Patel, Elyse M. Cornett, Amnon A. Berger, Jamal Hasoon, Hisham Kassem, Jai Won Jung, Giovanni F. Ramírez, Paola Colon Fugueroa, Neil R. Singhal, Jaehong Song, Adam M. Kaye, Alan D. Kaye, Sarang S. Koushik, Natalie H. Strand, Latha Ganti
Format: Article
Language:English
Published: Open Medical Publishing 2023-01-01
Series:Health Psychology Research
Online Access:https://doi.org/10.52965/001c.67853
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author Jacquelin Peck
Justin Zeien
Megha Patel
Elyse M. Cornett
Amnon A. Berger
Jamal Hasoon
Hisham Kassem
Jai Won Jung
Giovanni F. Ramírez
Paola Colon Fugueroa
Neil R. Singhal
Jaehong Song
Adam M. Kaye
Alan D. Kaye
Sarang S. Koushik
Natalie H. Strand
Latha Ganti
author_facet Jacquelin Peck
Justin Zeien
Megha Patel
Elyse M. Cornett
Amnon A. Berger
Jamal Hasoon
Hisham Kassem
Jai Won Jung
Giovanni F. Ramírez
Paola Colon Fugueroa
Neil R. Singhal
Jaehong Song
Adam M. Kaye
Alan D. Kaye
Sarang S. Koushik
Natalie H. Strand
Latha Ganti
author_sort Jacquelin Peck
collection DOAJ
description This is a review of the latest and seminal evidence in pediatric migraine. It covers the etiology and pathophysiology known today, and then will review treatment options, efficacy and safety, quality of data and indications. Though migraine is usually regarded as an infliction in adults, it is not uncommon in the pediatric population and affects up to 8% of children. Children may experience migraine differently than adults, and present not only with headache but also frequent gastrointestinal symptoms. They are frequently shorter in duration than in adults. Traditional migraine treatment in adults is less effective in children. In this population, adjunct therapies -- such as interventional techniques -- should be considered when traditional treatment fails, including Botulinum Toxin A (BTA) injections, peripheral nerve and ganglion blocks. BTA injections are FDA approved for migraine prophylaxis in adults, but currently not in children; however, recent evidence shows efficacy and safety in pediatric migraine management. Nerve blocks stop nociceptive afferent fibers through injection of local anesthetics, and it may be associated with the local injection of corticosteroids. Although more common in adults, recent data suggests they are safe and effective in children and adolescents. Blocking the sphenopalatine ganglion can be achieved through nasal approach, and achieves a similar action by blocking the entire ganglion. Interventional techniques may provide a key component in the alleviation of this otherwise debilitating chronic migraine pain. Though most studies have been performed in adults, new studies provide encouraging results for treatment in children.
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spelling doaj-art-5e3e8a3dc3ff4f24b437e404314090342025-02-11T20:30:39ZengOpen Medical PublishingHealth Psychology Research2420-81242023-01-01105Review of Interventional Therapies for Refractory Pediatric MigraineJacquelin PeckJustin ZeienMegha PatelElyse M. CornettAmnon A. BergerJamal HasoonHisham KassemJai Won JungGiovanni F. RamírezPaola Colon FugueroaNeil R. SinghalJaehong SongAdam M. KayeAlan D. KayeSarang S. KoushikNatalie H. StrandLatha GantiThis is a review of the latest and seminal evidence in pediatric migraine. It covers the etiology and pathophysiology known today, and then will review treatment options, efficacy and safety, quality of data and indications. Though migraine is usually regarded as an infliction in adults, it is not uncommon in the pediatric population and affects up to 8% of children. Children may experience migraine differently than adults, and present not only with headache but also frequent gastrointestinal symptoms. They are frequently shorter in duration than in adults. Traditional migraine treatment in adults is less effective in children. In this population, adjunct therapies -- such as interventional techniques -- should be considered when traditional treatment fails, including Botulinum Toxin A (BTA) injections, peripheral nerve and ganglion blocks. BTA injections are FDA approved for migraine prophylaxis in adults, but currently not in children; however, recent evidence shows efficacy and safety in pediatric migraine management. Nerve blocks stop nociceptive afferent fibers through injection of local anesthetics, and it may be associated with the local injection of corticosteroids. Although more common in adults, recent data suggests they are safe and effective in children and adolescents. Blocking the sphenopalatine ganglion can be achieved through nasal approach, and achieves a similar action by blocking the entire ganglion. Interventional techniques may provide a key component in the alleviation of this otherwise debilitating chronic migraine pain. Though most studies have been performed in adults, new studies provide encouraging results for treatment in children.https://doi.org/10.52965/001c.67853
spellingShingle Jacquelin Peck
Justin Zeien
Megha Patel
Elyse M. Cornett
Amnon A. Berger
Jamal Hasoon
Hisham Kassem
Jai Won Jung
Giovanni F. Ramírez
Paola Colon Fugueroa
Neil R. Singhal
Jaehong Song
Adam M. Kaye
Alan D. Kaye
Sarang S. Koushik
Natalie H. Strand
Latha Ganti
Review of Interventional Therapies for Refractory Pediatric Migraine
Health Psychology Research
title Review of Interventional Therapies for Refractory Pediatric Migraine
title_full Review of Interventional Therapies for Refractory Pediatric Migraine
title_fullStr Review of Interventional Therapies for Refractory Pediatric Migraine
title_full_unstemmed Review of Interventional Therapies for Refractory Pediatric Migraine
title_short Review of Interventional Therapies for Refractory Pediatric Migraine
title_sort review of interventional therapies for refractory pediatric migraine
url https://doi.org/10.52965/001c.67853
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