Advances in selective hydrogenation of nitrobenzene toward p-aminophenol

p-Aminophenol is an important intermediate for dyestuff, medical and rubber. Selective hydrogenation of nitrobenzene is a green and environmentally friendly preparation process for the p-aminophenol synthesis. In this review, we first introduce the catalytic performances of a series of catalysts for...

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Main Authors: Jinzhi Lu, Hao Wang, Xiao Cai, Yan Zhu
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Sustainable Chemistry for Climate Action
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772826925000173
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author Jinzhi Lu
Hao Wang
Xiao Cai
Yan Zhu
author_facet Jinzhi Lu
Hao Wang
Xiao Cai
Yan Zhu
author_sort Jinzhi Lu
collection DOAJ
description p-Aminophenol is an important intermediate for dyestuff, medical and rubber. Selective hydrogenation of nitrobenzene is a green and environmentally friendly preparation process for the p-aminophenol synthesis. In this review, we first introduce the catalytic performances of a series of catalysts for the selective hydrogenation of nitrobenzene to p-aminophenol. Then the typical reaction pathways of nitrobenzene hydrogenation toward p-aminophenol are proposed. Moreover, various acid reaction systems that can replace sulfuric acid are described. Finally, the existential problems of this reaction and future efforts are pointed out. It is anticipated that the review can provide perspectives on the design rules of highly active and highly selective catalysts for the selective hydrogenation of nitrobenzene to p-aminophenol.
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institution Kabale University
issn 2772-8269
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publishDate 2025-06-01
publisher Elsevier
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series Sustainable Chemistry for Climate Action
spelling doaj-art-5e2143106fce462a86f07f9929cd93b12025-08-20T03:44:55ZengElsevierSustainable Chemistry for Climate Action2772-82692025-06-01610007210.1016/j.scca.2025.100072Advances in selective hydrogenation of nitrobenzene toward p-aminophenolJinzhi Lu0Hao Wang1Xiao Cai2Yan Zhu3School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, ChinaSchool of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, ChinaSchool of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, ChinaCorresponding author.; School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, Chinap-Aminophenol is an important intermediate for dyestuff, medical and rubber. Selective hydrogenation of nitrobenzene is a green and environmentally friendly preparation process for the p-aminophenol synthesis. In this review, we first introduce the catalytic performances of a series of catalysts for the selective hydrogenation of nitrobenzene to p-aminophenol. Then the typical reaction pathways of nitrobenzene hydrogenation toward p-aminophenol are proposed. Moreover, various acid reaction systems that can replace sulfuric acid are described. Finally, the existential problems of this reaction and future efforts are pointed out. It is anticipated that the review can provide perspectives on the design rules of highly active and highly selective catalysts for the selective hydrogenation of nitrobenzene to p-aminophenol.http://www.sciencedirect.com/science/article/pii/S2772826925000173p-AminophenolSelective hydrogenationCatalystsReaction pathwayAcid media
spellingShingle Jinzhi Lu
Hao Wang
Xiao Cai
Yan Zhu
Advances in selective hydrogenation of nitrobenzene toward p-aminophenol
Sustainable Chemistry for Climate Action
p-Aminophenol
Selective hydrogenation
Catalysts
Reaction pathway
Acid media
title Advances in selective hydrogenation of nitrobenzene toward p-aminophenol
title_full Advances in selective hydrogenation of nitrobenzene toward p-aminophenol
title_fullStr Advances in selective hydrogenation of nitrobenzene toward p-aminophenol
title_full_unstemmed Advances in selective hydrogenation of nitrobenzene toward p-aminophenol
title_short Advances in selective hydrogenation of nitrobenzene toward p-aminophenol
title_sort advances in selective hydrogenation of nitrobenzene toward p aminophenol
topic p-Aminophenol
Selective hydrogenation
Catalysts
Reaction pathway
Acid media
url http://www.sciencedirect.com/science/article/pii/S2772826925000173
work_keys_str_mv AT jinzhilu advancesinselectivehydrogenationofnitrobenzenetowardpaminophenol
AT haowang advancesinselectivehydrogenationofnitrobenzenetowardpaminophenol
AT xiaocai advancesinselectivehydrogenationofnitrobenzenetowardpaminophenol
AT yanzhu advancesinselectivehydrogenationofnitrobenzenetowardpaminophenol