THE LONG-TERM RESULTS OF OCCULT BREAST CARCINOMA TREATMENT
In breast cancer patients, axillary status continues to be the most powerful predictor of survival. This article contains retrospective and prospective analysis for 5-year survival, regional and distant recurrences of 35 patients with occult breast cancer (OBC) presenting as isolated axillary nodal...
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| Format: | Article |
| Language: | English |
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Bashkir State Medical University
2017-01-01
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| Series: | Креативная хирургия и онкология |
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| Online Access: | https://www.surgonco.ru/jour/article/view/7 |
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| author | T. V. Kuklenko |
| author_facet | T. V. Kuklenko |
| author_sort | T. V. Kuklenko |
| collection | DOAJ |
| description | In breast cancer patients, axillary status continues to be the most powerful predictor of survival. This article contains retrospective and prospective analysis for 5-year survival, regional and distant recurrences of 35 patients with occult breast cancer (OBC) presenting as isolated axillary nodal metastasis TxN1-2M0 (I group) and 150 cases of node-positive palpable breast cancer (PBC) T1-3N1-2M0 (II group) during the period from 1997 to 2012 according the materials of Chelyabinsk regional oncology dispensary. The aim of this investigation is to compare prognoses of these groups patients after complex treatment to optimistic treating and diagnostic tactic of OBC. Five-year Kaplan-Meier estimate of overall survival among groups of our patients who had had lymph node metastasis status as N2 in I and II group had been allocated as 46,6% and 63,3% respectively (p=0,02). Five-year distant recurrences of disease among groups of our patients who had had lymph node metastasis status as N2 in I and II group had been allocated as 66,6% and 51,6% respectively (p=0,04). The differences observed between patients of these groups were statistically significant. The OBC prognosis is worse than PBC in N2 subgroup that demand more aggressive therapy for patients of I group. |
| format | Article |
| id | doaj-art-5e1cc7a54e914c709890192efd8a9b40 |
| institution | Kabale University |
| issn | 2076-3093 2307-0501 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Bashkir State Medical University |
| record_format | Article |
| series | Креативная хирургия и онкология |
| spelling | doaj-art-5e1cc7a54e914c709890192efd8a9b402025-08-20T03:40:00ZengBashkir State Medical UniversityКреативная хирургия и онкология2076-30932307-05012017-01-0101-2172110.24060/2076-3093-2014-0-1-2-17-217THE LONG-TERM RESULTS OF OCCULT BREAST CARCINOMA TREATMENTT. V. Kuklenko0Regional Oncological DispensaryIn breast cancer patients, axillary status continues to be the most powerful predictor of survival. This article contains retrospective and prospective analysis for 5-year survival, regional and distant recurrences of 35 patients with occult breast cancer (OBC) presenting as isolated axillary nodal metastasis TxN1-2M0 (I group) and 150 cases of node-positive palpable breast cancer (PBC) T1-3N1-2M0 (II group) during the period from 1997 to 2012 according the materials of Chelyabinsk regional oncology dispensary. The aim of this investigation is to compare prognoses of these groups patients after complex treatment to optimistic treating and diagnostic tactic of OBC. Five-year Kaplan-Meier estimate of overall survival among groups of our patients who had had lymph node metastasis status as N2 in I and II group had been allocated as 46,6% and 63,3% respectively (p=0,02). Five-year distant recurrences of disease among groups of our patients who had had lymph node metastasis status as N2 in I and II group had been allocated as 66,6% and 51,6% respectively (p=0,04). The differences observed between patients of these groups were statistically significant. The OBC prognosis is worse than PBC in N2 subgroup that demand more aggressive therapy for patients of I group.https://www.surgonco.ru/jour/article/view/7occult breast cancerpalpable breast cancerlymph nodeaxillary lymph node metastasisprognosis |
| spellingShingle | T. V. Kuklenko THE LONG-TERM RESULTS OF OCCULT BREAST CARCINOMA TREATMENT Креативная хирургия и онкология occult breast cancer palpable breast cancer lymph node axillary lymph node metastasis prognosis |
| title | THE LONG-TERM RESULTS OF OCCULT BREAST CARCINOMA TREATMENT |
| title_full | THE LONG-TERM RESULTS OF OCCULT BREAST CARCINOMA TREATMENT |
| title_fullStr | THE LONG-TERM RESULTS OF OCCULT BREAST CARCINOMA TREATMENT |
| title_full_unstemmed | THE LONG-TERM RESULTS OF OCCULT BREAST CARCINOMA TREATMENT |
| title_short | THE LONG-TERM RESULTS OF OCCULT BREAST CARCINOMA TREATMENT |
| title_sort | long term results of occult breast carcinoma treatment |
| topic | occult breast cancer palpable breast cancer lymph node axillary lymph node metastasis prognosis |
| url | https://www.surgonco.ru/jour/article/view/7 |
| work_keys_str_mv | AT tvkuklenko thelongtermresultsofoccultbreastcarcinomatreatment AT tvkuklenko longtermresultsofoccultbreastcarcinomatreatment |