Modelling protein-protein interactions for the design of vaccine chimeric antigens with protective epitopes.

Modelling protein-protein interactions for the design of vaccine chimeric antigens with protective epitopes.

Ticks and tick-borne diseases are a growing burden worldwide and vaccines are effective control interventions. Vaccine formulations with tick antigens such as BM86/BM95 (BM) and Subolesin (SUB) have shown reduction in tick fitness and infestation in immunized hosts. However, antigen combination is a...

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Main Authors: Marinela Contreras, Marta Rafael, Isidro Sobrino, Consuelo Almazán, Juan J Pastor Comín, James J Valdés, Carlos Roberto Prudencio, Daniel Ferreira de Lima Neto, Veniamin A Borin, Pratul K Agarwal, Paul D Kasaija, Rubén Fernández-Melgar, Justus Rutaisire, José de la Fuente
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0318439
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https://doi.org/10.1371/journal.pone.0318439

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