Comparison of Visual Evoked Potential Components In Female Patients of Primary Open Angle Glaucoma with Age Matched Control Females
Objective: To compare the P100 latency and P100 amplitude of pattern reversal visual evoked potential VEP in a cohort of female patients having primary open angle glaucoma (POAG) with those of age matched control females. Materials: This rural hospital based study was conducted in the Neurophysiolog...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2013-07-01
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| Series: | Delhi Journal of Ophthalmology |
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| Online Access: | https://journals.lww.com/10.7869/djo.2013.5 |
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| author | Ruchi Kothari Pradeep Bokariya Smita Singh Ramji Singh |
| author_facet | Ruchi Kothari Pradeep Bokariya Smita Singh Ramji Singh |
| author_sort | Ruchi Kothari |
| collection | DOAJ |
| description | Objective:
To compare the P100 latency and P100 amplitude of pattern reversal visual evoked potential VEP in a cohort of female patients having primary open angle glaucoma (POAG) with those of age matched control females.
Materials:
This rural hospital based study was conducted in the Neurophysiology unit of the Department of Physiology of our institute. The study comprised of pattern reversal visual evoked potential (PRVEP) recordings from 244 eyes (92 POAG eyes and 152 control eyes).
Study Design:
This was a comparative case-control study.
Methods:
VEP recordings were performed with the stimulus configuration consisting of the transient pattern reversal method in which a black and white checker board was generated (full field) and displayed on VEP Monitor by an electronic pattern regenerator inbuilt in an Evoked Potential Recorder (RMS EMG EP MARK II, Recorders and Medicare Systems, Chandigarh). VEP waveform, latencies and amplitude were measured in all subjects.
Results:
The mean age of POAG females (N=46) was 55 ± 10.50 years and the mean age of control females (N=76) was 54.30 ± 10.62 years. The age range for both the groups was 40-79 years. On comparison among all the age groups, the mean P100 latency of POAG patients was 98.13±6.39 msec and the mean P100 latency of the controls was 97.14 ± 4.46 msec. The mean amplitude of P100 in POAG patients was less than that of control subjects in the almost all the age groups. It was 4.48 ± 1.39 μV in POAG cases as compared to 6.20±2.02 μV in the controls of the age group 60-69 years and it was 3.76 ± 2.35 μV in POAG cases as compared to 4.36± 0.67μV in the controls of the age group 70-79 years.
Conclusion:
Age wise and gender wise case control comparison of PRVEP components in our study subjects revealed that the eyes of females of POAG group have shown longer P100 latencies and produced diminished amplitude than the control eyes. The inter-eye difference of all the VEP parameters in the POAG group was significantly greater than those of controls. While in the control group, there was negligible inter-ocular difference between the two eyes of the same sex. |
| format | Article |
| id | doaj-art-5e18c5d576824f6d9b834d43829b6830 |
| institution | Kabale University |
| issn | 0972-0200 2454-2784 |
| language | English |
| publishDate | 2013-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Delhi Journal of Ophthalmology |
| spelling | doaj-art-5e18c5d576824f6d9b834d43829b68302025-08-20T03:52:29ZengWolters Kluwer Medknow PublicationsDelhi Journal of Ophthalmology0972-02002454-27842013-07-01241283310.7869/djo.2013.5Comparison of Visual Evoked Potential Components In Female Patients of Primary Open Angle Glaucoma with Age Matched Control FemalesRuchi KothariPradeep BokariyaSmita SinghRamji SinghObjective: To compare the P100 latency and P100 amplitude of pattern reversal visual evoked potential VEP in a cohort of female patients having primary open angle glaucoma (POAG) with those of age matched control females. Materials: This rural hospital based study was conducted in the Neurophysiology unit of the Department of Physiology of our institute. The study comprised of pattern reversal visual evoked potential (PRVEP) recordings from 244 eyes (92 POAG eyes and 152 control eyes). Study Design: This was a comparative case-control study. Methods: VEP recordings were performed with the stimulus configuration consisting of the transient pattern reversal method in which a black and white checker board was generated (full field) and displayed on VEP Monitor by an electronic pattern regenerator inbuilt in an Evoked Potential Recorder (RMS EMG EP MARK II, Recorders and Medicare Systems, Chandigarh). VEP waveform, latencies and amplitude were measured in all subjects. Results: The mean age of POAG females (N=46) was 55 ± 10.50 years and the mean age of control females (N=76) was 54.30 ± 10.62 years. The age range for both the groups was 40-79 years. On comparison among all the age groups, the mean P100 latency of POAG patients was 98.13±6.39 msec and the mean P100 latency of the controls was 97.14 ± 4.46 msec. The mean amplitude of P100 in POAG patients was less than that of control subjects in the almost all the age groups. It was 4.48 ± 1.39 μV in POAG cases as compared to 6.20±2.02 μV in the controls of the age group 60-69 years and it was 3.76 ± 2.35 μV in POAG cases as compared to 4.36± 0.67μV in the controls of the age group 70-79 years. Conclusion: Age wise and gender wise case control comparison of PRVEP components in our study subjects revealed that the eyes of females of POAG group have shown longer P100 latencies and produced diminished amplitude than the control eyes. The inter-eye difference of all the VEP parameters in the POAG group was significantly greater than those of controls. While in the control group, there was negligible inter-ocular difference between the two eyes of the same sex.https://journals.lww.com/10.7869/djo.2013.5open angle glaucomafemalesp100 latencyp100 amplitude |
| spellingShingle | Ruchi Kothari Pradeep Bokariya Smita Singh Ramji Singh Comparison of Visual Evoked Potential Components In Female Patients of Primary Open Angle Glaucoma with Age Matched Control Females Delhi Journal of Ophthalmology open angle glaucoma females p100 latency p100 amplitude |
| title | Comparison of Visual Evoked Potential Components In Female Patients of Primary Open Angle Glaucoma with Age Matched Control Females |
| title_full | Comparison of Visual Evoked Potential Components In Female Patients of Primary Open Angle Glaucoma with Age Matched Control Females |
| title_fullStr | Comparison of Visual Evoked Potential Components In Female Patients of Primary Open Angle Glaucoma with Age Matched Control Females |
| title_full_unstemmed | Comparison of Visual Evoked Potential Components In Female Patients of Primary Open Angle Glaucoma with Age Matched Control Females |
| title_short | Comparison of Visual Evoked Potential Components In Female Patients of Primary Open Angle Glaucoma with Age Matched Control Females |
| title_sort | comparison of visual evoked potential components in female patients of primary open angle glaucoma with age matched control females |
| topic | open angle glaucoma females p100 latency p100 amplitude |
| url | https://journals.lww.com/10.7869/djo.2013.5 |
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