The synthesis of 4-arylcoumarines via cu-catalyzed arylation 4-hydroxycoumarine with the substituted phenylboronic acids
In this research, the catalytic activity of Fe3O4@SiO2-NNO-CuII nanocomposite was investigated in Suzuki coupling reaction of 4- tosylcoumarine with various substituted arylboronic acids. This reusable copper nanocatalyst activated CO bond and with the exit of tosylate group, CC bond was formed be...
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Elsevier
2025-07-01
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| Series: | Results in Chemistry |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715625003029 |
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| author | F. Rafiee O. Nazari |
| author_facet | F. Rafiee O. Nazari |
| author_sort | F. Rafiee |
| collection | DOAJ |
| description | In this research, the catalytic activity of Fe3O4@SiO2-NNO-CuII nanocomposite was investigated in Suzuki coupling reaction of 4- tosylcoumarine with various substituted arylboronic acids. This reusable copper nanocatalyst activated CO bond and with the exit of tosylate group, CC bond was formed between 4-position of coumarin and arylboronic acid derivative. The substituted 4-arylcoumarines were obtained in high yields and short reaction times under mild reaction. The prepared nanocatalyst was easily separated from the reaction mixture using an external magnet and could reused in the next reaction runs for at least 4 cycles. |
| format | Article |
| id | doaj-art-5e11a0f28fe749e5b3f4c981bceb6fcb |
| institution | DOAJ |
| issn | 2211-7156 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Chemistry |
| spelling | doaj-art-5e11a0f28fe749e5b3f4c981bceb6fcb2025-08-20T03:02:36ZengElsevierResults in Chemistry2211-71562025-07-011610231910.1016/j.rechem.2025.102319The synthesis of 4-arylcoumarines via cu-catalyzed arylation 4-hydroxycoumarine with the substituted phenylboronic acidsF. Rafiee0O. Nazari1Corresponding author.; Department of Organic Chemistry, Faculty of Chemistry, Alzahra University, Tehran, IranDepartment of Organic Chemistry, Faculty of Chemistry, Alzahra University, Tehran, IranIn this research, the catalytic activity of Fe3O4@SiO2-NNO-CuII nanocomposite was investigated in Suzuki coupling reaction of 4- tosylcoumarine with various substituted arylboronic acids. This reusable copper nanocatalyst activated CO bond and with the exit of tosylate group, CC bond was formed between 4-position of coumarin and arylboronic acid derivative. The substituted 4-arylcoumarines were obtained in high yields and short reaction times under mild reaction. The prepared nanocatalyst was easily separated from the reaction mixture using an external magnet and could reused in the next reaction runs for at least 4 cycles.http://www.sciencedirect.com/science/article/pii/S2211715625003029CC bond formationCu-catalyzed4-hydroxycoumarine4-arylcoumarineSilica-coated magnetic nanoparticles |
| spellingShingle | F. Rafiee O. Nazari The synthesis of 4-arylcoumarines via cu-catalyzed arylation 4-hydroxycoumarine with the substituted phenylboronic acids Results in Chemistry CC bond formation Cu-catalyzed 4-hydroxycoumarine 4-arylcoumarine Silica-coated magnetic nanoparticles |
| title | The synthesis of 4-arylcoumarines via cu-catalyzed arylation 4-hydroxycoumarine with the substituted phenylboronic acids |
| title_full | The synthesis of 4-arylcoumarines via cu-catalyzed arylation 4-hydroxycoumarine with the substituted phenylboronic acids |
| title_fullStr | The synthesis of 4-arylcoumarines via cu-catalyzed arylation 4-hydroxycoumarine with the substituted phenylboronic acids |
| title_full_unstemmed | The synthesis of 4-arylcoumarines via cu-catalyzed arylation 4-hydroxycoumarine with the substituted phenylboronic acids |
| title_short | The synthesis of 4-arylcoumarines via cu-catalyzed arylation 4-hydroxycoumarine with the substituted phenylboronic acids |
| title_sort | synthesis of 4 arylcoumarines via cu catalyzed arylation 4 hydroxycoumarine with the substituted phenylboronic acids |
| topic | CC bond formation Cu-catalyzed 4-hydroxycoumarine 4-arylcoumarine Silica-coated magnetic nanoparticles |
| url | http://www.sciencedirect.com/science/article/pii/S2211715625003029 |
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