Long-Term Survival of a Patient with Invasive Signet-Ring Cell Carcinoma of the Urinary Bladder Managed by Combined S-1 and Cisplatin Adjuvant Chemotherapy
Primary signet-ring cell carcinoma of the urinary bladder is extremely rare and patient survival is very poor. The disease usually presents at advanced stages because the cancer progresses rapidly. The only option for effective treatment is radical cystectomy, and no effective chemotherapy has been...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Urology |
| Online Access: | http://dx.doi.org/10.1155/2013/915874 |
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| author | Takashi Hamakawa Yoshiyuki Kojima Taku Naiki Yasue Kubota Takahiro Yasui Keiichi Tozawa Yutaro Hayashi Kenjiro Kohri |
| author_facet | Takashi Hamakawa Yoshiyuki Kojima Taku Naiki Yasue Kubota Takahiro Yasui Keiichi Tozawa Yutaro Hayashi Kenjiro Kohri |
| author_sort | Takashi Hamakawa |
| collection | DOAJ |
| description | Primary signet-ring cell carcinoma of the urinary bladder is extremely rare and patient survival is very poor. The disease usually presents at advanced stages because the cancer progresses rapidly. The only option for effective treatment is radical cystectomy, and no effective chemotherapy has been established for this variant. We report a case of signet-ring cell carcinoma of the urinary bladder with a long-term survival of 90 months owing to radical cystectomy and combination adjuvant chemotherapy with S-1 and cisplatin. To our knowledge, this is the first report to demonstrate the long-term therapeutic activity of combination S-1 and cisplatin adjuvant chemotherapy against invasive signet-ring cell carcinoma of the urinary bladder. |
| format | Article |
| id | doaj-art-5e0f8d0632c24e2a880df1cee8a0907c |
| institution | OA Journals |
| issn | 2090-696X 2090-6978 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Urology |
| spelling | doaj-art-5e0f8d0632c24e2a880df1cee8a0907c2025-08-20T02:06:03ZengWileyCase Reports in Urology2090-696X2090-69782013-01-01201310.1155/2013/915874915874Long-Term Survival of a Patient with Invasive Signet-Ring Cell Carcinoma of the Urinary Bladder Managed by Combined S-1 and Cisplatin Adjuvant ChemotherapyTakashi Hamakawa0Yoshiyuki Kojima1Taku Naiki2Yasue Kubota3Takahiro Yasui4Keiichi Tozawa5Yutaro Hayashi6Kenjiro Kohri7Department of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-chou, Mizuho-ku, Nagoya 467-8601, JapanDepartment of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-chou, Mizuho-ku, Nagoya 467-8601, JapanDepartment of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-chou, Mizuho-ku, Nagoya 467-8601, JapanDepartment of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-chou, Mizuho-ku, Nagoya 467-8601, JapanDepartment of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-chou, Mizuho-ku, Nagoya 467-8601, JapanDepartment of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-chou, Mizuho-ku, Nagoya 467-8601, JapanDepartment of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-chou, Mizuho-ku, Nagoya 467-8601, JapanDepartment of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-chou, Mizuho-ku, Nagoya 467-8601, JapanPrimary signet-ring cell carcinoma of the urinary bladder is extremely rare and patient survival is very poor. The disease usually presents at advanced stages because the cancer progresses rapidly. The only option for effective treatment is radical cystectomy, and no effective chemotherapy has been established for this variant. We report a case of signet-ring cell carcinoma of the urinary bladder with a long-term survival of 90 months owing to radical cystectomy and combination adjuvant chemotherapy with S-1 and cisplatin. To our knowledge, this is the first report to demonstrate the long-term therapeutic activity of combination S-1 and cisplatin adjuvant chemotherapy against invasive signet-ring cell carcinoma of the urinary bladder.http://dx.doi.org/10.1155/2013/915874 |
| spellingShingle | Takashi Hamakawa Yoshiyuki Kojima Taku Naiki Yasue Kubota Takahiro Yasui Keiichi Tozawa Yutaro Hayashi Kenjiro Kohri Long-Term Survival of a Patient with Invasive Signet-Ring Cell Carcinoma of the Urinary Bladder Managed by Combined S-1 and Cisplatin Adjuvant Chemotherapy Case Reports in Urology |
| title | Long-Term Survival of a Patient with Invasive Signet-Ring Cell Carcinoma of the Urinary Bladder Managed by Combined S-1 and Cisplatin Adjuvant Chemotherapy |
| title_full | Long-Term Survival of a Patient with Invasive Signet-Ring Cell Carcinoma of the Urinary Bladder Managed by Combined S-1 and Cisplatin Adjuvant Chemotherapy |
| title_fullStr | Long-Term Survival of a Patient with Invasive Signet-Ring Cell Carcinoma of the Urinary Bladder Managed by Combined S-1 and Cisplatin Adjuvant Chemotherapy |
| title_full_unstemmed | Long-Term Survival of a Patient with Invasive Signet-Ring Cell Carcinoma of the Urinary Bladder Managed by Combined S-1 and Cisplatin Adjuvant Chemotherapy |
| title_short | Long-Term Survival of a Patient with Invasive Signet-Ring Cell Carcinoma of the Urinary Bladder Managed by Combined S-1 and Cisplatin Adjuvant Chemotherapy |
| title_sort | long term survival of a patient with invasive signet ring cell carcinoma of the urinary bladder managed by combined s 1 and cisplatin adjuvant chemotherapy |
| url | http://dx.doi.org/10.1155/2013/915874 |
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