DNA Polymerase: Structural Homology, Conformational Dynamics, and the Effects of Carcinogenic DNA Adducts
DNA replication is vital for an organism to proliferate and lying at the heart of this process is the enzyme DNA polymerase. Most DNA polymerases have a similar three dimensional fold, akin to a human right hand, despite differences in sequence homology. This structural homology would predict a rela...
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Main Authors: | Richard G. Federley, Louis J. Romano |
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Format: | Article |
Language: | English |
Published: |
Wiley
2010-01-01
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Series: | Journal of Nucleic Acids |
Online Access: | http://dx.doi.org/10.4061/2010/457176 |
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