The production and development of vaccines for ornithobacterium rhinotracheale infection in commercial broilers
<b>Aim:</b> The purpose of this study was to prepare bivalent inactive Ornithobacterium rhinotracheale [O. rhinotarcheale) bacterin vaccines, to measure the levels of antibodies against antigens in blood sera and to determine the efficacies of different O. rhinotracheale vaccines in broi...
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| Format: | Article |
| Language: | English |
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Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
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| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=574 |
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| author | Osman Erganiş Hasan Hüseyin Hadimli Kursat Kav Zafer Sayin |
| author_facet | Osman Erganiş Hasan Hüseyin Hadimli Kursat Kav Zafer Sayin |
| author_sort | Osman Erganiş |
| collection | DOAJ |
| description | <b>Aim:</b> The purpose of this study was to prepare bivalent inactive Ornithobacterium rhinotracheale [O. rhinotarcheale) bacterin vaccines, to measure the levels of antibodies against antigens in blood sera and to determine the efficacies of different O. rhinotracheale vaccines in broilers.<p>
<b>Materials and Methods:</b> The bivalent inactivated O. rhinotracheale bacterin vaccines were prepared from O. rhinotracheale serotype A and B strains using aluminium hydroxide (Al[OH]<sub>3</sub>), mineral oil (MO), aluminium hydroxide + ginseng (Al[OH]<sub>3</sub> + G) and mineral oil + ginseng (MO + G). After the sterility and the safety tests, laboratory efficiencies of vaccines (challange/protection and serological potency) were controlled on the broilers (vaccinated at first day with a dose of 0.1 mL).<p>
<b>Results:</b> According to the challenge results, all the vaccines were found to be effective as 100% for broilers. The vaccine containing mineral oil and ginseng (MO + G) as adjuvant induced significantly greater humoral immune response to the antigens than others.<p>
<b>Conclusion:</b> The study showed that vaccination of broilers chicken at the first day age may effectively protect against O. rhinotracheale infections. |
| format | Article |
| id | doaj-art-5e02a47e38ce4239952a7eae4e4493a0 |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-5e02a47e38ce4239952a7eae4e4493a02024-12-02T09:05:29ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-195327299105574The production and development of vaccines for ornithobacterium rhinotracheale infection in commercial broilersOsman ErganişHasan Hüseyin HadimliKursat KavZafer Sayin<b>Aim:</b> The purpose of this study was to prepare bivalent inactive Ornithobacterium rhinotracheale [O. rhinotarcheale) bacterin vaccines, to measure the levels of antibodies against antigens in blood sera and to determine the efficacies of different O. rhinotracheale vaccines in broilers.<p> <b>Materials and Methods:</b> The bivalent inactivated O. rhinotracheale bacterin vaccines were prepared from O. rhinotracheale serotype A and B strains using aluminium hydroxide (Al[OH]<sub>3</sub>), mineral oil (MO), aluminium hydroxide + ginseng (Al[OH]<sub>3</sub> + G) and mineral oil + ginseng (MO + G). After the sterility and the safety tests, laboratory efficiencies of vaccines (challange/protection and serological potency) were controlled on the broilers (vaccinated at first day with a dose of 0.1 mL).<p> <b>Results:</b> According to the challenge results, all the vaccines were found to be effective as 100% for broilers. The vaccine containing mineral oil and ginseng (MO + G) as adjuvant induced significantly greater humoral immune response to the antigens than others.<p> <b>Conclusion:</b> The study showed that vaccination of broilers chicken at the first day age may effectively protect against O. rhinotracheale infections.http://eurasianjvetsci.org/pdf.php3?id=574ornithobacterium rhinotrachealebroiler chickenvaccineginseng |
| spellingShingle | Osman Erganiş Hasan Hüseyin Hadimli Kursat Kav Zafer Sayin The production and development of vaccines for ornithobacterium rhinotracheale infection in commercial broilers Eurasian Journal of Veterinary Sciences ornithobacterium rhinotracheale broiler chicken vaccine ginseng |
| title | The production and development of vaccines for ornithobacterium rhinotracheale infection in commercial broilers |
| title_full | The production and development of vaccines for ornithobacterium rhinotracheale infection in commercial broilers |
| title_fullStr | The production and development of vaccines for ornithobacterium rhinotracheale infection in commercial broilers |
| title_full_unstemmed | The production and development of vaccines for ornithobacterium rhinotracheale infection in commercial broilers |
| title_short | The production and development of vaccines for ornithobacterium rhinotracheale infection in commercial broilers |
| title_sort | production and development of vaccines for ornithobacterium rhinotracheale infection in commercial broilers |
| topic | ornithobacterium rhinotracheale broiler chicken vaccine ginseng |
| url | http://eurasianjvetsci.org/pdf.php3?id=574 |
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