PFAPA syndrome: a rare cause of periodic fever

PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, adenopathy) is characterized by abrupt onset of fever, malaise, aphthous stomatitis, tonsillitis, pharyngitis and cervical adenopathy. The age of onset of the disease is four years, with a range of 6 months to 7 years. The synd...

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Main Authors: Hanifi Kurtaran, Ahmet Karadağ, Ferhat Catal, Davut Aktaş
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2004-10-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/2834
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author Hanifi Kurtaran
Ahmet Karadağ
Ferhat Catal
Davut Aktaş
author_facet Hanifi Kurtaran
Ahmet Karadağ
Ferhat Catal
Davut Aktaş
author_sort Hanifi Kurtaran
collection DOAJ
description PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, adenopathy) is characterized by abrupt onset of fever, malaise, aphthous stomatitis, tonsillitis, pharyngitis and cervical adenopathy. The age of onset of the disease is four years, with a range of 6 months to 7 years. The syndrome is sporadic and nonhereditary. Long-term sequelae do not develop. A nine- year-old boy presented with sore throat, fever and oral aphthae. After taking a throat culture, he was prescribed oral antipyretic and was called for a follow-up visit the next day. As the culture result was negative, he was given a single dose prednisolone with the suspected diagnosis of PFAPA. Twenty-four hours later his temperature was 36.8 degrees C, with all his complaints regressed. Twenty-two days later the patient was again admitted to our hospital with the same complaints. Again, single dose oral prednisolone was given after a throat culture. On the next day the patient was free of all symptoms and the culture was again normal. To our knowledge this is the first PFAPA case report from Turkey in the literature.
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publishDate 2004-10-01
publisher Hacettepe University Institute of Child Health
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series The Turkish Journal of Pediatrics
spelling doaj-art-5dfd7c50b9344047af0329e074b33e2d2025-08-20T02:01:57ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212004-10-01464PFAPA syndrome: a rare cause of periodic feverHanifi Kurtaran0Ahmet KaradağFerhat CatalDavut AktaşDepartment of Otorhinolaryngology, Fatih University Faculty of Medicine, Ankara, Turkey. PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, adenopathy) is characterized by abrupt onset of fever, malaise, aphthous stomatitis, tonsillitis, pharyngitis and cervical adenopathy. The age of onset of the disease is four years, with a range of 6 months to 7 years. The syndrome is sporadic and nonhereditary. Long-term sequelae do not develop. A nine- year-old boy presented with sore throat, fever and oral aphthae. After taking a throat culture, he was prescribed oral antipyretic and was called for a follow-up visit the next day. As the culture result was negative, he was given a single dose prednisolone with the suspected diagnosis of PFAPA. Twenty-four hours later his temperature was 36.8 degrees C, with all his complaints regressed. Twenty-two days later the patient was again admitted to our hospital with the same complaints. Again, single dose oral prednisolone was given after a throat culture. On the next day the patient was free of all symptoms and the culture was again normal. To our knowledge this is the first PFAPA case report from Turkey in the literature. https://turkjpediatr.org/article/view/2834
spellingShingle Hanifi Kurtaran
Ahmet Karadağ
Ferhat Catal
Davut Aktaş
PFAPA syndrome: a rare cause of periodic fever
The Turkish Journal of Pediatrics
title PFAPA syndrome: a rare cause of periodic fever
title_full PFAPA syndrome: a rare cause of periodic fever
title_fullStr PFAPA syndrome: a rare cause of periodic fever
title_full_unstemmed PFAPA syndrome: a rare cause of periodic fever
title_short PFAPA syndrome: a rare cause of periodic fever
title_sort pfapa syndrome a rare cause of periodic fever
url https://turkjpediatr.org/article/view/2834
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