Complex treatment of allergic eye diseases using interferon alfa-2b and loratadine gel for topical and external use

Aimis to determine the efficacy of Allergoferon® — combined medicine composed of interferon alfa-2b and loratadine gel for topical and external use — in ocular allergies treatment.Materials and methods. 60 patients with allergic eye diseases were treated. Allergoferon® gel applied QID on upper and l...

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Main Authors: A. V. Surov, A. G. Zaspina
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2014-07-01
Series:Oftalʹmologiâ
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Online Access:https://www.ophthalmojournal.com/opht/article/view/37
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author A. V. Surov,
A. G. Zaspina
author_facet A. V. Surov,
A. G. Zaspina
author_sort A. V. Surov,
collection DOAJ
description Aimis to determine the efficacy of Allergoferon® — combined medicine composed of interferon alfa-2b and loratadine gel for topical and external use — in ocular allergies treatment.Materials and methods. 60 patients with allergic eye diseases were treated. Allergoferon® gel applied QID on upper and lower eyelids was used as a first-line therapy. Efficacy was measured using the following criteria: chemozis, eyelid edema, conjunctival redness and discharge, the presence of conjunctival follicles and papillae. All symptoms were scored using a 4‑point scale (0 = none, 1 = mild, 2 = moderate, 3 = severe).Results. Topical administration of Allergoferon® was associated with significant symptoms reduction, i.e., chemozis by 82 %, eyelid edema by 91 %, conjunctival redness by 79 %, eyelid redness by 88 %, conjunctival discharge by 95 %, the presence of conjunctival follicles and papillae by 76 %.Conclusion. Allergoferon® gel for topical and external use quickly reduces tissue allergic reactions and, consequently, terms of treatment. This medication is highly-effective as a therapy of ocular allergies owing to its antihistamine, anti-inflammatory and anti-exudative effects.
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spelling doaj-art-5dfd772396e8402e9a7380a5ec6dbfc42025-08-20T04:00:27ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452014-07-01111626510.18008/1816-5095-2014-1-62-6537Complex treatment of allergic eye diseases using interferon alfa-2b and loratadine gel for topical and external useA. V. Surov,0A. G. Zaspina1Omsk state medical academyOmsk state medical academyAimis to determine the efficacy of Allergoferon® — combined medicine composed of interferon alfa-2b and loratadine gel for topical and external use — in ocular allergies treatment.Materials and methods. 60 patients with allergic eye diseases were treated. Allergoferon® gel applied QID on upper and lower eyelids was used as a first-line therapy. Efficacy was measured using the following criteria: chemozis, eyelid edema, conjunctival redness and discharge, the presence of conjunctival follicles and papillae. All symptoms were scored using a 4‑point scale (0 = none, 1 = mild, 2 = moderate, 3 = severe).Results. Topical administration of Allergoferon® was associated with significant symptoms reduction, i.e., chemozis by 82 %, eyelid edema by 91 %, conjunctival redness by 79 %, eyelid redness by 88 %, conjunctival discharge by 95 %, the presence of conjunctival follicles and papillae by 76 %.Conclusion. Allergoferon® gel for topical and external use quickly reduces tissue allergic reactions and, consequently, terms of treatment. This medication is highly-effective as a therapy of ocular allergies owing to its antihistamine, anti-inflammatory and anti-exudative effects.https://www.ophthalmojournal.com/opht/article/view/37allergic conjunctivitisinterferon alfa-2bloratadineallergoferon
spellingShingle A. V. Surov,
A. G. Zaspina
Complex treatment of allergic eye diseases using interferon alfa-2b and loratadine gel for topical and external use
Oftalʹmologiâ
allergic conjunctivitis
interferon alfa-2b
loratadine
allergoferon
title Complex treatment of allergic eye diseases using interferon alfa-2b and loratadine gel for topical and external use
title_full Complex treatment of allergic eye diseases using interferon alfa-2b and loratadine gel for topical and external use
title_fullStr Complex treatment of allergic eye diseases using interferon alfa-2b and loratadine gel for topical and external use
title_full_unstemmed Complex treatment of allergic eye diseases using interferon alfa-2b and loratadine gel for topical and external use
title_short Complex treatment of allergic eye diseases using interferon alfa-2b and loratadine gel for topical and external use
title_sort complex treatment of allergic eye diseases using interferon alfa 2b and loratadine gel for topical and external use
topic allergic conjunctivitis
interferon alfa-2b
loratadine
allergoferon
url https://www.ophthalmojournal.com/opht/article/view/37
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AT agzaspina complextreatmentofallergiceyediseasesusinginterferonalfa2bandloratadinegelfortopicalandexternaluse