Very late stent thrombosis of bare-metal coronary stent nine years after primary percutaneous coronary intervention
Introduction. Stent thrombosis (ST) in clinical practice can be classified according to time of onset as early (0–30 days after stent implantation), which is further divided into acute (< 24 hours) and subacute (1–30 days), late (> 30 days) and very late (> 12 months). Myocardial reinfactio...
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2016-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501600053D.pdf |
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| author | Đurić Predrag Obradović Slobodan Stajić Zoran Spasić Marijan Matunović Radomir Romanović Radoslav Đenić Nemanja Jović Zoran |
| author_facet | Đurić Predrag Obradović Slobodan Stajić Zoran Spasić Marijan Matunović Radomir Romanović Radoslav Đenić Nemanja Jović Zoran |
| author_sort | Đurić Predrag |
| collection | DOAJ |
| description | Introduction. Stent thrombosis (ST) in clinical practice can be classified according to time of onset as early (0–30 days after stent implantation), which is further divided into acute (< 24 hours) and subacute (1–30 days), late (> 30 days) and very late (> 12 months). Myocardial reinfaction due to very late ST in a patient receiving antithrombotic therapy is very rare, and potentially fatal. The procedure alone and related mechanical factors seem to be associated with acute/subacute ST. On the other hand, in-stent neoathero-sclerosis, inflammation, premature cessation of antiplatelet therapy, as well as stent fracture, stent malapposition, un-covered stent struts may play role in late/very late ST. Some findings implicate that the etiology of very late ST of bare-metal stent (BMS) is quite different from those following drug-eluting stent (DES) implantation. Case report. We presented a 56-year old male with acute inferoposterior ST segment elevation myocardial infarction (STEMI) related to very late stent thrombosis, 9 years after BMS implantation, despite antithrombotic therapy. Thrombus aspiration was successfully performed followed by percutaneous coronary intervention (PCI) with implantation of DES into the pre-viously implanted two stents to solve the in-stent restenosis. Conclusion. Very late stent thrombosis, although fortu-nately very rare, not completely understood, might cause myocardial reinfaction, but could be successfully treated with thrombus aspiration followed by primary PCI. Very late ST in the presented patient might be connected with neointimal plaque rupture, followed by thrombotic events. |
| format | Article |
| id | doaj-art-5deb2274726d413fb16a4e2a388cee64 |
| institution | Kabale University |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-5deb2274726d413fb16a4e2a388cee642025-08-20T03:34:44ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202016-01-0173877477810.2298/VSP141222053D0042-84501600053DVery late stent thrombosis of bare-metal coronary stent nine years after primary percutaneous coronary interventionĐurić Predrag0Obradović Slobodan1Stajić Zoran2Spasić Marijan3Matunović Radomir4Romanović Radoslav5Đenić Nemanja6Jović Zoran7Military Medical Academy, Clinic of Cardiology, Clinic of Urgent Medicine, BelgradeMilitary Medical Academy, Clinic of Cardiology, Clinic of Urgent Medicine, BelgradeMilitary Medical Academy, Clinic of Cardiology, Clinic of Urgent Medicine, BelgradeMilitary Medical Academy, Clinic of Cardiology, Clinic of Urgent Medicine, BelgradeMilitary Medical Academy, Clinic of Cardiology, Clinic of Urgent Medicine, BelgradeMilitary Medical Academy, Clinic of Cardiology, Clinic of Urgent Medicine, BelgradeMilitary Medical Academy, Clinic of Cardiology, Clinic of Urgent Medicine, BelgradeMilitary Medical Academy, Clinic of Cardiology, Clinic of Urgent Medicine, BelgradeIntroduction. Stent thrombosis (ST) in clinical practice can be classified according to time of onset as early (0–30 days after stent implantation), which is further divided into acute (< 24 hours) and subacute (1–30 days), late (> 30 days) and very late (> 12 months). Myocardial reinfaction due to very late ST in a patient receiving antithrombotic therapy is very rare, and potentially fatal. The procedure alone and related mechanical factors seem to be associated with acute/subacute ST. On the other hand, in-stent neoathero-sclerosis, inflammation, premature cessation of antiplatelet therapy, as well as stent fracture, stent malapposition, un-covered stent struts may play role in late/very late ST. Some findings implicate that the etiology of very late ST of bare-metal stent (BMS) is quite different from those following drug-eluting stent (DES) implantation. Case report. We presented a 56-year old male with acute inferoposterior ST segment elevation myocardial infarction (STEMI) related to very late stent thrombosis, 9 years after BMS implantation, despite antithrombotic therapy. Thrombus aspiration was successfully performed followed by percutaneous coronary intervention (PCI) with implantation of DES into the pre-viously implanted two stents to solve the in-stent restenosis. Conclusion. Very late stent thrombosis, although fortu-nately very rare, not completely understood, might cause myocardial reinfaction, but could be successfully treated with thrombus aspiration followed by primary PCI. Very late ST in the presented patient might be connected with neointimal plaque rupture, followed by thrombotic events.http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501600053D.pdfstentsdrug-eluting stentsthrombosismyocardial infarctionangioplasty, baloon |
| spellingShingle | Đurić Predrag Obradović Slobodan Stajić Zoran Spasić Marijan Matunović Radomir Romanović Radoslav Đenić Nemanja Jović Zoran Very late stent thrombosis of bare-metal coronary stent nine years after primary percutaneous coronary intervention Vojnosanitetski Pregled stents drug-eluting stents thrombosis myocardial infarction angioplasty, baloon |
| title | Very late stent thrombosis of bare-metal coronary stent nine years after primary percutaneous coronary intervention |
| title_full | Very late stent thrombosis of bare-metal coronary stent nine years after primary percutaneous coronary intervention |
| title_fullStr | Very late stent thrombosis of bare-metal coronary stent nine years after primary percutaneous coronary intervention |
| title_full_unstemmed | Very late stent thrombosis of bare-metal coronary stent nine years after primary percutaneous coronary intervention |
| title_short | Very late stent thrombosis of bare-metal coronary stent nine years after primary percutaneous coronary intervention |
| title_sort | very late stent thrombosis of bare metal coronary stent nine years after primary percutaneous coronary intervention |
| topic | stents drug-eluting stents thrombosis myocardial infarction angioplasty, baloon |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501600053D.pdf |
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