The neuro-glial properties of adipose-derived adult stromal (ADAS) cells are not regulated by Notch 1 and are not derived from neural crest lineage.

The neuro-glial properties of adipose-derived adult stromal (ADAS) cells are not regulated by Notch 1 and are not derived from neural crest lineage.

We investigated whether adipose-derived adult stromal (ADAS) are of neural crest origin and the extent to which Notch 1 regulates their growth and differentiation. Mouse ADAS cells cultured in media formulated for neural stem cells (NSC) displayed limited capacity for self-renewal, clonogenicity, an...

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Main Authors: Philip C Wrage, Thi Tran, Khai To, Edward W Keefer, Kelly A Ruhn, John Hong, Supriya Hattangadi, Isaac Treviño, Malú G Tansey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0001453&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0001453&type=printable

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