Trifarotene: A Novel Therapeutic Option for Acne

Acne vulgaris, or acne, is a prevailing cutaneous predicament that customarily crops up on the face, neck, and trunk in the forms of comedones, papules, pustules, and nodules. According to epidemiologic explorations, acne affects 9.4% of the global population, making it the eighth most common diseas...

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Main Author: Piyu Parth Naik
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Dermatology Research and Practice
Online Access:http://dx.doi.org/10.1155/2022/1504303
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author Piyu Parth Naik
author_facet Piyu Parth Naik
author_sort Piyu Parth Naik
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description Acne vulgaris, or acne, is a prevailing cutaneous predicament that customarily crops up on the face, neck, and trunk in the forms of comedones, papules, pustules, and nodules. According to epidemiologic explorations, acne affects 9.4% of the global population, making it the eighth most common disease globally. Acne perturbs up to 85% of adolescents, while it is periodically misconceived as an ailment that affects teenagers only; nonetheless, it also affects myriad adults. Acne has well-documented psychosocial ramifications, including adverse effects on self-perception, mental health, and social functioning. Trifarotene is basically a novel fourth-generation locally applied retinoid approved for the first time in the regimens of both face and truncal acnes. The exclusive topical retinoid that adheres precisely to RAR-gamma, the epidermis' most frequent isoform, is trifarotene, approved in October 2019. The current review evaluates the role of trifarotene in treating acne.
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spelling doaj-art-5de3a4a77a6e4d9aaf1f39f4f184fe712025-08-20T03:34:44ZengWileyDermatology Research and Practice1687-61132022-01-01202210.1155/2022/1504303Trifarotene: A Novel Therapeutic Option for AcnePiyu Parth Naik0Department of dermatologyAcne vulgaris, or acne, is a prevailing cutaneous predicament that customarily crops up on the face, neck, and trunk in the forms of comedones, papules, pustules, and nodules. According to epidemiologic explorations, acne affects 9.4% of the global population, making it the eighth most common disease globally. Acne perturbs up to 85% of adolescents, while it is periodically misconceived as an ailment that affects teenagers only; nonetheless, it also affects myriad adults. Acne has well-documented psychosocial ramifications, including adverse effects on self-perception, mental health, and social functioning. Trifarotene is basically a novel fourth-generation locally applied retinoid approved for the first time in the regimens of both face and truncal acnes. The exclusive topical retinoid that adheres precisely to RAR-gamma, the epidermis' most frequent isoform, is trifarotene, approved in October 2019. The current review evaluates the role of trifarotene in treating acne.http://dx.doi.org/10.1155/2022/1504303
spellingShingle Piyu Parth Naik
Trifarotene: A Novel Therapeutic Option for Acne
Dermatology Research and Practice
title Trifarotene: A Novel Therapeutic Option for Acne
title_full Trifarotene: A Novel Therapeutic Option for Acne
title_fullStr Trifarotene: A Novel Therapeutic Option for Acne
title_full_unstemmed Trifarotene: A Novel Therapeutic Option for Acne
title_short Trifarotene: A Novel Therapeutic Option for Acne
title_sort trifarotene a novel therapeutic option for acne
url http://dx.doi.org/10.1155/2022/1504303
work_keys_str_mv AT piyuparthnaik trifaroteneanoveltherapeuticoptionforacne