Preclinical evaluation of 64Cu-labeled cetuximab in immuno-PET for detecting sentinel lymph node metastasis in epidermal growth factor receptor-positive breast cancer

Preclinical evaluation of 64Cu-labeled cetuximab in immuno-PET for detecting sentinel lymph node metastasis in epidermal growth factor receptor-positive breast cancer

Abstract Background Despite advances in breast cancer imaging, reliable detection of sentinel lymph node (SLN) metastasis remains challenging. This study aimed to determine the ability of immuno-positron emission tomography (PET) using 64Cu-labeled cetuximab to detect SLN metastasis in a model of ep...

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Bibliographic Details
Main Authors: Takeshi Usui, Tomohiro Miyake, Tadashi Watabe, Hiroki Kato, Yukie Yoshii, Sadahiro Naka, Kaori Abe, Misato Masuyama, Nanae Masunaga, Tetsuhiro Yoshinami, Masami Tsukabe, Yoshiaki Sota, Tomonori Tanei, Masafumi Shimoda, Kenzo Shimazu
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Breast Cancer Research
Subjects:
Immuno-PET
Sentinel lymph node metastasis
Epidermal growth factor receptor
Breast cancer
Online Access:https://doi.org/10.1186/s13058-025-01972-4
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