Protease-activated receptor 2 deficient mice develop less angiotensin II induced left ventricular hypertrophy but more cardiac fibrosis.

<h4>Aims</h4>Activation of Protease Activated Receptor 2 (PAR2) has been shown to be involved in regulation of injury-related processes including inflammation, fibrosis and hypertrophy. In this study we will investigate the role of PAR2 in cardiac injury in a mouse model of hypertension...

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Bibliographic Details
Main Authors: Albrecht Meyer Zu Schwabedissen, Silvia Vergarajauregui, Marko Bertog, Kerstin Amann, Felix B Engel, Christoph Daniel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0310095
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