Medication Adherence and Common Barriers for Caregivers of Preschool Children with Pediatric Glaucoma

Purpose. To investigate the medication adherence among caregivers of preschool children with pediatric glaucoma and to elucidate common barriers leading to poor adherence. Methods. A cross-sectional study. Caregivers of preschool children with pediatric glaucoma completed a questionnaire on demograp...

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Main Authors: Zitian Liu, Yuning Zhang, Pingping Liu, Wenxin Yang, Xinyan Li, Yimin Zhong, Yangfan Yang, Xing Liu, Huiming Xiao, Minbin Yu, Wenmin Huang
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2022/6389822
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author Zitian Liu
Yuning Zhang
Pingping Liu
Wenxin Yang
Xinyan Li
Yimin Zhong
Yangfan Yang
Xing Liu
Huiming Xiao
Minbin Yu
Wenmin Huang
author_facet Zitian Liu
Yuning Zhang
Pingping Liu
Wenxin Yang
Xinyan Li
Yimin Zhong
Yangfan Yang
Xing Liu
Huiming Xiao
Minbin Yu
Wenmin Huang
author_sort Zitian Liu
collection DOAJ
description Purpose. To investigate the medication adherence among caregivers of preschool children with pediatric glaucoma and to elucidate common barriers leading to poor adherence. Methods. A cross-sectional study. Caregivers of preschool children with pediatric glaucoma completed a questionnaire on demographic information of caregivers, demographic and disease characteristics of children, caregivers-reported medication adherence (by an adapted Morisky Adherence Scale), and possible 13 barriers. Results. Overall 132 questionnaires were considered valid. Thirty-six percent of all reported poor medication adherence. Caregivers’ age and self-evaluated knowledge about pediatric glaucoma showed a significant difference between the adherent and nonadherent groups (P<0.05). Nineteen percent of all reported only one barrier as important, 65% cited multiple barriers, and 16% cited no barriers. Anxiety and depression were cited as important by most caregivers in both groups. Univariate logistic regression analysis demonstrated that difficulty with the acquisition of medications (OR, 2.5; 95% CI, 1.1–5.7; P=0.025), difficulty with medication schedule (OR, 2.3; 95% CI, 1.0–5.0; P=0.043), and high expenses for medications (OR, 4.8; 95% CI, 1.4–15.9; P=0.011) were significantly associated with higher odds of poor adherence. Conclusions. Over one-third of caregivers of preschool children with pediatric glaucoma were in poor medication adherence. Nearly two-thirds of caregivers cited multiple barriers simultaneously as important hindrances to medication usage. Anxiety and depression, difficulty with the acquisition of medications, difficulty with the medication schedule, and high expenses for medications were prominent barriers. Individualized solutions should be provided according to reported barriers by each caregiver and the other most common barriers.
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spelling doaj-art-5ddc72943f1c46d38859fb93d3badeb72025-08-20T02:06:03ZengWileyJournal of Ophthalmology2090-00582022-01-01202210.1155/2022/6389822Medication Adherence and Common Barriers for Caregivers of Preschool Children with Pediatric GlaucomaZitian Liu0Yuning Zhang1Pingping Liu2Wenxin Yang3Xinyan Li4Yimin Zhong5Yangfan Yang6Xing Liu7Huiming Xiao8Minbin Yu9Wenmin Huang10State Key Laboratory of OphthalmologyState Key Laboratory of OphthalmologyState Key Laboratory of OphthalmologyState Key Laboratory of OphthalmologyState Key Laboratory of OphthalmologyState Key Laboratory of OphthalmologyState Key Laboratory of OphthalmologyState Key Laboratory of OphthalmologyState Key Laboratory of OphthalmologyState Key Laboratory of OphthalmologyState Key Laboratory of OphthalmologyPurpose. To investigate the medication adherence among caregivers of preschool children with pediatric glaucoma and to elucidate common barriers leading to poor adherence. Methods. A cross-sectional study. Caregivers of preschool children with pediatric glaucoma completed a questionnaire on demographic information of caregivers, demographic and disease characteristics of children, caregivers-reported medication adherence (by an adapted Morisky Adherence Scale), and possible 13 barriers. Results. Overall 132 questionnaires were considered valid. Thirty-six percent of all reported poor medication adherence. Caregivers’ age and self-evaluated knowledge about pediatric glaucoma showed a significant difference between the adherent and nonadherent groups (P<0.05). Nineteen percent of all reported only one barrier as important, 65% cited multiple barriers, and 16% cited no barriers. Anxiety and depression were cited as important by most caregivers in both groups. Univariate logistic regression analysis demonstrated that difficulty with the acquisition of medications (OR, 2.5; 95% CI, 1.1–5.7; P=0.025), difficulty with medication schedule (OR, 2.3; 95% CI, 1.0–5.0; P=0.043), and high expenses for medications (OR, 4.8; 95% CI, 1.4–15.9; P=0.011) were significantly associated with higher odds of poor adherence. Conclusions. Over one-third of caregivers of preschool children with pediatric glaucoma were in poor medication adherence. Nearly two-thirds of caregivers cited multiple barriers simultaneously as important hindrances to medication usage. Anxiety and depression, difficulty with the acquisition of medications, difficulty with the medication schedule, and high expenses for medications were prominent barriers. Individualized solutions should be provided according to reported barriers by each caregiver and the other most common barriers.http://dx.doi.org/10.1155/2022/6389822
spellingShingle Zitian Liu
Yuning Zhang
Pingping Liu
Wenxin Yang
Xinyan Li
Yimin Zhong
Yangfan Yang
Xing Liu
Huiming Xiao
Minbin Yu
Wenmin Huang
Medication Adherence and Common Barriers for Caregivers of Preschool Children with Pediatric Glaucoma
Journal of Ophthalmology
title Medication Adherence and Common Barriers for Caregivers of Preschool Children with Pediatric Glaucoma
title_full Medication Adherence and Common Barriers for Caregivers of Preschool Children with Pediatric Glaucoma
title_fullStr Medication Adherence and Common Barriers for Caregivers of Preschool Children with Pediatric Glaucoma
title_full_unstemmed Medication Adherence and Common Barriers for Caregivers of Preschool Children with Pediatric Glaucoma
title_short Medication Adherence and Common Barriers for Caregivers of Preschool Children with Pediatric Glaucoma
title_sort medication adherence and common barriers for caregivers of preschool children with pediatric glaucoma
url http://dx.doi.org/10.1155/2022/6389822
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