Challenges in Predicting the Filtration Performance of a Novel Sewn Mask: Scale-up from Filter Holder to Mannequin Measurements

Abstract Novel designs and materials for filtering face-piece respirators (FFRs) have been disseminated in response to shortages during the COVID-19 pandemic. Since filtration efficiency depends on particle diameter and air face velocity, the relevance of material filtration or prototype fit data de...

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Main Authors: Audrey J. Dang, Benjamin M. Kumfer, J. Tyler Bertroche, Jane Olson Glidden, Christopher R. Oxford, Udayabhanu Jammalamadaka, Mary Ruppert-Stroescu, Alexander R. Scott, Jason A. Morris, Connie Gan, Jesse Hu, Bradley King, David I. A. Dhanraj, Shruti Choudhary, Pratim Biswas, Richard L. Axelbaum, Kathleen W. Meacham, Brent J. Williams
Format: Article
Language:English
Published: Springer 2021-04-01
Series:Aerosol and Air Quality Research
Subjects:
Online Access:https://doi.org/10.4209/aaqr.200629
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author Audrey J. Dang
Benjamin M. Kumfer
J. Tyler Bertroche
Jane Olson Glidden
Christopher R. Oxford
Udayabhanu Jammalamadaka
Mary Ruppert-Stroescu
Alexander R. Scott
Jason A. Morris
Connie Gan
Jesse Hu
Bradley King
David I. A. Dhanraj
Shruti Choudhary
Pratim Biswas
Richard L. Axelbaum
Kathleen W. Meacham
Brent J. Williams
author_facet Audrey J. Dang
Benjamin M. Kumfer
J. Tyler Bertroche
Jane Olson Glidden
Christopher R. Oxford
Udayabhanu Jammalamadaka
Mary Ruppert-Stroescu
Alexander R. Scott
Jason A. Morris
Connie Gan
Jesse Hu
Bradley King
David I. A. Dhanraj
Shruti Choudhary
Pratim Biswas
Richard L. Axelbaum
Kathleen W. Meacham
Brent J. Williams
author_sort Audrey J. Dang
collection DOAJ
description Abstract Novel designs and materials for filtering face-piece respirators (FFRs) have been disseminated in response to shortages during the COVID-19 pandemic. Since filtration efficiency depends on particle diameter and air face velocity, the relevance of material filtration or prototype fit data depends on test conditions. We investigate whether characterizing a material in a filter holder at a range of face velocities enabled precise prediction of the filtration performance of a novel sewn mask design. While larger particles (> 500 nm) are more relevant for inhalation exposure to respiratory emissions, we compare this mask and a N95 FFR (as a control) with smaller particles more similar to those in the N95 test method. Sewn from sterilization wrap, our mask (sealed to a mannequin head with silicone) filters 85 ± 1% of 136 nm particles (NaCl, 85 L min−1) and passes quantitative fit tests for 4 of 6 volunteers, representing intermediate protection between a surgical mask and N95 FFR. Filter holder material measurements overpredict the sewn mask’s filtration efficiency by 8.2% (95% CI 7.4–9.1%) (136 or 200 nm). While testing flat material in a filter holder enables comparison between materials, filtration performance does not precisely scale-up from filter holder to mannequin tests. Testing full prototypes at relevant conditions is crucial if an improvised design is intended as a substitute for a commercial surgical mask or FFR.
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spelling doaj-art-5dd7676fb528428c908b95453124e6b02025-02-09T12:19:38ZengSpringerAerosol and Air Quality Research1680-85842071-14092021-04-0121611510.4209/aaqr.200629Challenges in Predicting the Filtration Performance of a Novel Sewn Mask: Scale-up from Filter Holder to Mannequin MeasurementsAudrey J. Dang0Benjamin M. Kumfer1J. Tyler Bertroche2Jane Olson Glidden3Christopher R. Oxford4Udayabhanu Jammalamadaka5Mary Ruppert-Stroescu6Alexander R. Scott7Jason A. Morris8Connie Gan9Jesse Hu10Bradley King11David I. A. Dhanraj12Shruti Choudhary13Pratim Biswas14Richard L. Axelbaum15Kathleen W. Meacham16Brent J. Williams17Center for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St LouisCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St LouisDepartment of Otolaryngology-Head & Neck Surgery, Washington University School of MedicineWeavers’ Guild of St. LouisCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St LouisMallinckrodt Institute of Radiology, Washington University in St. Louis School of MedicineSam Fox School of Design and Visual Arts, Washington University in St. LouisWashington University in St. Louis School of MedicineWashington University in St. Louis School of MedicineWashington University in St. Louis School of MedicineWashington University in St. Louis School of MedicineDivision of Environmental Health & Safety, Washington University in St. LouisCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St LouisCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St LouisCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St LouisCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St LouisDepartment of Anesthesiology, Washington University in St. Louis School of MedicineCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St LouisAbstract Novel designs and materials for filtering face-piece respirators (FFRs) have been disseminated in response to shortages during the COVID-19 pandemic. Since filtration efficiency depends on particle diameter and air face velocity, the relevance of material filtration or prototype fit data depends on test conditions. We investigate whether characterizing a material in a filter holder at a range of face velocities enabled precise prediction of the filtration performance of a novel sewn mask design. While larger particles (> 500 nm) are more relevant for inhalation exposure to respiratory emissions, we compare this mask and a N95 FFR (as a control) with smaller particles more similar to those in the N95 test method. Sewn from sterilization wrap, our mask (sealed to a mannequin head with silicone) filters 85 ± 1% of 136 nm particles (NaCl, 85 L min−1) and passes quantitative fit tests for 4 of 6 volunteers, representing intermediate protection between a surgical mask and N95 FFR. Filter holder material measurements overpredict the sewn mask’s filtration efficiency by 8.2% (95% CI 7.4–9.1%) (136 or 200 nm). While testing flat material in a filter holder enables comparison between materials, filtration performance does not precisely scale-up from filter holder to mannequin tests. Testing full prototypes at relevant conditions is crucial if an improvised design is intended as a substitute for a commercial surgical mask or FFR.https://doi.org/10.4209/aaqr.200629RespiratorFiltrationFace velocityCOVID-19Mask
spellingShingle Audrey J. Dang
Benjamin M. Kumfer
J. Tyler Bertroche
Jane Olson Glidden
Christopher R. Oxford
Udayabhanu Jammalamadaka
Mary Ruppert-Stroescu
Alexander R. Scott
Jason A. Morris
Connie Gan
Jesse Hu
Bradley King
David I. A. Dhanraj
Shruti Choudhary
Pratim Biswas
Richard L. Axelbaum
Kathleen W. Meacham
Brent J. Williams
Challenges in Predicting the Filtration Performance of a Novel Sewn Mask: Scale-up from Filter Holder to Mannequin Measurements
Aerosol and Air Quality Research
Respirator
Filtration
Face velocity
COVID-19
Mask
title Challenges in Predicting the Filtration Performance of a Novel Sewn Mask: Scale-up from Filter Holder to Mannequin Measurements
title_full Challenges in Predicting the Filtration Performance of a Novel Sewn Mask: Scale-up from Filter Holder to Mannequin Measurements
title_fullStr Challenges in Predicting the Filtration Performance of a Novel Sewn Mask: Scale-up from Filter Holder to Mannequin Measurements
title_full_unstemmed Challenges in Predicting the Filtration Performance of a Novel Sewn Mask: Scale-up from Filter Holder to Mannequin Measurements
title_short Challenges in Predicting the Filtration Performance of a Novel Sewn Mask: Scale-up from Filter Holder to Mannequin Measurements
title_sort challenges in predicting the filtration performance of a novel sewn mask scale up from filter holder to mannequin measurements
topic Respirator
Filtration
Face velocity
COVID-19
Mask
url https://doi.org/10.4209/aaqr.200629
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