Advancing forensic investigations based on TiO2/Bi2O3 electrochemical sensor for precise potassium estimation in vitreous humor
In the domain of criminal investigations, the integration of nanotechnology has emerged as a transformative force, mirroring advancements across diverse scientific realms. This study focuses on leveraging the synergistic potential of a bimetallic TiO2/Bi2O3 nano-composite to meticulously evaluate vi...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844025002440 |
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| author | Zulfiqar Ali Buzdar Hamza Ali Maria Munir Naveed A. Shad Allah Rakha Anam Munawar |
| author_facet | Zulfiqar Ali Buzdar Hamza Ali Maria Munir Naveed A. Shad Allah Rakha Anam Munawar |
| author_sort | Zulfiqar Ali Buzdar |
| collection | DOAJ |
| description | In the domain of criminal investigations, the integration of nanotechnology has emerged as a transformative force, mirroring advancements across diverse scientific realms. This study focuses on leveraging the synergistic potential of a bimetallic TiO2/Bi2O3 nano-composite to meticulously evaluate vitreous potassium levels in human cadavers. The designed TiO2/Bi2O3 nano-composite exhibits a finely structured morphology, characterized by diminutive sheet-like formations spanning the nano-scale dimension of 20–250 nm. Through rigorous analysis, we establish a robust linear correlation (R2 = 0.992) between the nanocomposite and potassium concentrations in postmortem vitreous samples. Notably, the nano-composite demonstrates an exceptional limit of detection at 0.001 nM, surpassing comparable materials and methodologies reported to date (FTIR, GC-MS and biochemical analysis) and provide measurement of time since death with a precision of 1 h. The elevated sensitivity of the nano-composite to potassium concentrations opens new possibilities for enhancing the accuracy and efficiency of forensic analyses, ultimately aiding in the pursuit of justice. |
| format | Article |
| id | doaj-art-5dd437c66ec2461180df6c9e3ad433cc |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-5dd437c66ec2461180df6c9e3ad433cc2025-02-02T05:28:25ZengElsevierHeliyon2405-84402025-01-01112e41864Advancing forensic investigations based on TiO2/Bi2O3 electrochemical sensor for precise potassium estimation in vitreous humorZulfiqar Ali Buzdar0Hamza Ali1Maria Munir2Naveed A. Shad3Allah Rakha4Anam Munawar5Department of Forensic Medicine/Medical Jurisprudence, University of Health Sciences, Lahore, PakistanForensic Medicine and Toxicology Department, Sahara Medical College, Narowal, PakistanForensic Medicine and Toxicology Department, Sahara Medical College, Narowal, PakistanNational Institute for Biotechnology & Genetic Engineering (NIBGE), Faisalabad, PakistanDepartment of Forensic Medicine/Medical Jurisprudence, University of Health Sciences, Lahore, Pakistan; Corresponding author.Department of Forensic Medicine/Medical Jurisprudence, University of Health Sciences, Lahore, Pakistan; Corresponding author.In the domain of criminal investigations, the integration of nanotechnology has emerged as a transformative force, mirroring advancements across diverse scientific realms. This study focuses on leveraging the synergistic potential of a bimetallic TiO2/Bi2O3 nano-composite to meticulously evaluate vitreous potassium levels in human cadavers. The designed TiO2/Bi2O3 nano-composite exhibits a finely structured morphology, characterized by diminutive sheet-like formations spanning the nano-scale dimension of 20–250 nm. Through rigorous analysis, we establish a robust linear correlation (R2 = 0.992) between the nanocomposite and potassium concentrations in postmortem vitreous samples. Notably, the nano-composite demonstrates an exceptional limit of detection at 0.001 nM, surpassing comparable materials and methodologies reported to date (FTIR, GC-MS and biochemical analysis) and provide measurement of time since death with a precision of 1 h. The elevated sensitivity of the nano-composite to potassium concentrations opens new possibilities for enhancing the accuracy and efficiency of forensic analyses, ultimately aiding in the pursuit of justice.http://www.sciencedirect.com/science/article/pii/S2405844025002440Vitreous potassiumForensicTiO2/Bi2O3 nano-compositeTime since death (TSD)Postmortem investigation (PMI) |
| spellingShingle | Zulfiqar Ali Buzdar Hamza Ali Maria Munir Naveed A. Shad Allah Rakha Anam Munawar Advancing forensic investigations based on TiO2/Bi2O3 electrochemical sensor for precise potassium estimation in vitreous humor Heliyon Vitreous potassium Forensic TiO2/Bi2O3 nano-composite Time since death (TSD) Postmortem investigation (PMI) |
| title | Advancing forensic investigations based on TiO2/Bi2O3 electrochemical sensor for precise potassium estimation in vitreous humor |
| title_full | Advancing forensic investigations based on TiO2/Bi2O3 electrochemical sensor for precise potassium estimation in vitreous humor |
| title_fullStr | Advancing forensic investigations based on TiO2/Bi2O3 electrochemical sensor for precise potassium estimation in vitreous humor |
| title_full_unstemmed | Advancing forensic investigations based on TiO2/Bi2O3 electrochemical sensor for precise potassium estimation in vitreous humor |
| title_short | Advancing forensic investigations based on TiO2/Bi2O3 electrochemical sensor for precise potassium estimation in vitreous humor |
| title_sort | advancing forensic investigations based on tio2 bi2o3 electrochemical sensor for precise potassium estimation in vitreous humor |
| topic | Vitreous potassium Forensic TiO2/Bi2O3 nano-composite Time since death (TSD) Postmortem investigation (PMI) |
| url | http://www.sciencedirect.com/science/article/pii/S2405844025002440 |
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