Members of the family <i>Lamiaceae</i> Lindl. as sources of medicinal plant raw materials to obtain neurotropic drugs
The aim of this work is to review and analyze the data published in the modern scientific literature obtained in pharmacological, pharmacognostic and pharmacotechnological studies of various types of raw materials obtained from members of the family Lamiaceae L., which were sources of biologically a...
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| Format: | Article |
| Language: | Russian |
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Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute
2020-05-01
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| Series: | Фармация и фармакология (Пятигорск) |
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| Online Access: | https://www.pharmpharm.ru/jour/article/view/620 |
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| author | Е. V. Zvezdina J. V. Dayronas I. I. Bochkareva I. N. Zilfikarov E. Yu. Babaeva E. V. Ferubko Z. A. Guseynova F. K. Serebryanaya S. R. Kaibova T. A. Ibragimov |
| author_facet | Е. V. Zvezdina J. V. Dayronas I. I. Bochkareva I. N. Zilfikarov E. Yu. Babaeva E. V. Ferubko Z. A. Guseynova F. K. Serebryanaya S. R. Kaibova T. A. Ibragimov |
| author_sort | Е. V. Zvezdina |
| collection | DOAJ |
| description | The aim of this work is to review and analyze the data published in the modern scientific literature obtained in pharmacological, pharmacognostic and pharmacotechnological studies of various types of raw materials obtained from members of the family Lamiaceae L., which were sources of biologically active substances, pharmaceutical substances, total extracts and the drugs – with a neurotropic activity.Materials and methods. For the review, we used the information of scientific literature from open and accessible sources of the last twenty years, located in the scientific and technical libraries of institutions, as well as in electronic databases: Elibrary, PubMed, Scopus, Cyberleninka, GoogleAcademy, J-Stage. The search inquiries were: the species of the family Lamiaceae (Russian and Latin), the samples of medicinal plant materials based on them as well as the names of the drugs and biologically active substances obtained from these raw materials.Results. When working with the sources of scientific information, the main attention was paid to pharmacologic tests performed during the studies on laboratory animals and proving the presence of neurotropic activity in the studied objects – essential oils and extracts from plant raw materials: aqueous, aqueous alcoholic, and methanol ones. It has been established that the potential of the therapeutic and preventive application of pharmaceutical substances and drugs based on the medicinal plant materials obtained from 30 genera members of the Lamiaceae family, remains unrealized despite the close attention of various researchers.Conclusion. This review comprised 71 species from 30 genera. Despite the significant level of the previous study presented in the analysis of this publication, an enormous potential of this family’s species remains unexplored. In the future, they can be of both – pharmacognostic and practical interest, in particular, in creation of new medicinal preparations of the neurotropic action based on them. |
| format | Article |
| id | doaj-art-5dc059e6389e4358b499e4eeb980e27c |
| institution | Kabale University |
| issn | 2307-9266 2413-2241 |
| language | Russian |
| publishDate | 2020-05-01 |
| publisher | Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute |
| record_format | Article |
| series | Фармация и фармакология (Пятигорск) |
| spelling | doaj-art-5dc059e6389e4358b499e4eeb980e27c2025-08-20T03:44:06ZrusVolgograd State Medical University, Pyatigorsk Medical and Pharmaceutical InstituteФармация и фармакология (Пятигорск)2307-92662413-22412020-05-018142810.19163/2307-9266-2020-8-1-4-28329Members of the family <i>Lamiaceae</i> Lindl. as sources of medicinal plant raw materials to obtain neurotropic drugsЕ. V. Zvezdina0J. V. Dayronas1I. I. Bochkareva2I. N. Zilfikarov3E. Yu. Babaeva4E. V. Ferubko5Z. A. Guseynova6F. K. Serebryanaya7S. R. Kaibova8T. A. Ibragimov9All-Russia Scientific Research Institute of Medicinal and Aromatic Plants (VILAR)Pyatigorsk Medical and Pharmaceutical Institute – a branch of Volgograd State Medical UniversityMaykop State Technological UniversityAll-Russia Scientific Research Institute of Medicinal and Aromatic Plants (VILAR); Maykop State Technological UniversityAll-Russia Scientific Research Institute of Medicinal and Aromatic Plants (VILAR)All-Russia Scientific Research Institute of Medicinal and Aromatic Plants (VILAR)Mountain Botanical Garden, Dagestan FIC RASPyatigorsk Medical and Pharmaceutical Institute – a branch of Volgograd State Medical UniversityDagestan State Medical UniversityDagestan State Medical University; Dagestan State UniversityThe aim of this work is to review and analyze the data published in the modern scientific literature obtained in pharmacological, pharmacognostic and pharmacotechnological studies of various types of raw materials obtained from members of the family Lamiaceae L., which were sources of biologically active substances, pharmaceutical substances, total extracts and the drugs – with a neurotropic activity.Materials and methods. For the review, we used the information of scientific literature from open and accessible sources of the last twenty years, located in the scientific and technical libraries of institutions, as well as in electronic databases: Elibrary, PubMed, Scopus, Cyberleninka, GoogleAcademy, J-Stage. The search inquiries were: the species of the family Lamiaceae (Russian and Latin), the samples of medicinal plant materials based on them as well as the names of the drugs and biologically active substances obtained from these raw materials.Results. When working with the sources of scientific information, the main attention was paid to pharmacologic tests performed during the studies on laboratory animals and proving the presence of neurotropic activity in the studied objects – essential oils and extracts from plant raw materials: aqueous, aqueous alcoholic, and methanol ones. It has been established that the potential of the therapeutic and preventive application of pharmaceutical substances and drugs based on the medicinal plant materials obtained from 30 genera members of the Lamiaceae family, remains unrealized despite the close attention of various researchers.Conclusion. This review comprised 71 species from 30 genera. Despite the significant level of the previous study presented in the analysis of this publication, an enormous potential of this family’s species remains unexplored. In the future, they can be of both – pharmacognostic and practical interest, in particular, in creation of new medicinal preparations of the neurotropic action based on them.https://www.pharmpharm.ru/jour/article/view/620literature review<i>lamiaceae</i> l.herbal medicinemedicinal plant materialsextractherbal formulation фитопрепаратmedicinal preparationpharmacognosypharmacologystressneurotropic activityanxiolytic effectsedative actionantidepressant actiongaba-α-receptorsbenzodiazepine receptors |
| spellingShingle | Е. V. Zvezdina J. V. Dayronas I. I. Bochkareva I. N. Zilfikarov E. Yu. Babaeva E. V. Ferubko Z. A. Guseynova F. K. Serebryanaya S. R. Kaibova T. A. Ibragimov Members of the family <i>Lamiaceae</i> Lindl. as sources of medicinal plant raw materials to obtain neurotropic drugs Фармация и фармакология (Пятигорск) literature review <i>lamiaceae</i> l. herbal medicine medicinal plant materials extract herbal formulation фитопрепарат medicinal preparation pharmacognosy pharmacology stress neurotropic activity anxiolytic effect sedative action antidepressant action gaba-α-receptors benzodiazepine receptors |
| title | Members of the family <i>Lamiaceae</i> Lindl. as sources of medicinal plant raw materials to obtain neurotropic drugs |
| title_full | Members of the family <i>Lamiaceae</i> Lindl. as sources of medicinal plant raw materials to obtain neurotropic drugs |
| title_fullStr | Members of the family <i>Lamiaceae</i> Lindl. as sources of medicinal plant raw materials to obtain neurotropic drugs |
| title_full_unstemmed | Members of the family <i>Lamiaceae</i> Lindl. as sources of medicinal plant raw materials to obtain neurotropic drugs |
| title_short | Members of the family <i>Lamiaceae</i> Lindl. as sources of medicinal plant raw materials to obtain neurotropic drugs |
| title_sort | members of the family i lamiaceae i lindl as sources of medicinal plant raw materials to obtain neurotropic drugs |
| topic | literature review <i>lamiaceae</i> l. herbal medicine medicinal plant materials extract herbal formulation фитопрепарат medicinal preparation pharmacognosy pharmacology stress neurotropic activity anxiolytic effect sedative action antidepressant action gaba-α-receptors benzodiazepine receptors |
| url | https://www.pharmpharm.ru/jour/article/view/620 |
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