The Assessment of Evidence Associating Nonsteroidal Anti-Inflammatory Drugs with Complications of Peptic Ulcerations
A causal relationship is now firmly established between nonsteroidal anti-inflammatory drug (NSAlD) use and the occurrence of peptic ulcer complications. In the United Kingdom, rising NSAID use has been matched by rises in ulcer mortality and perforation rates, particularly in older women. It is not...
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| Format: | Article |
| Language: | English |
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Wiley
1990-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1990/728604 |
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| _version_ | 1832553746732679168 |
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| author | MJS Langman |
| author_facet | MJS Langman |
| author_sort | MJS Langman |
| collection | DOAJ |
| description | A causal relationship is now firmly established between nonsteroidal
anti-inflammatory drug (NSAlD) use and the occurrence of peptic ulcer
complications. In the United Kingdom, rising NSAID use has been matched by
rises in ulcer mortality and perforation rates, particularly in older women. It is
not likely, however, that drug use accounts for the entire increase. The reasons
why some people develop ulcer complications and others do not are poorly
understood. It is plausible to propose that other factors, such as history of ulcer
or indigestion, current smoking, and alcohol consumption, might raise this risk;
however, supportive evidence is lacking. |
| format | Article |
| id | doaj-art-5dbb360714a6496b809289d38e933797 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 1990-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-5dbb360714a6496b809289d38e9337972025-02-03T05:53:19ZengWileyCanadian Journal of Gastroenterology0835-79001990-01-0143919410.1155/1990/728604The Assessment of Evidence Associating Nonsteroidal Anti-Inflammatory Drugs with Complications of Peptic UlcerationsMJS LangmanA causal relationship is now firmly established between nonsteroidal anti-inflammatory drug (NSAlD) use and the occurrence of peptic ulcer complications. In the United Kingdom, rising NSAID use has been matched by rises in ulcer mortality and perforation rates, particularly in older women. It is not likely, however, that drug use accounts for the entire increase. The reasons why some people develop ulcer complications and others do not are poorly understood. It is plausible to propose that other factors, such as history of ulcer or indigestion, current smoking, and alcohol consumption, might raise this risk; however, supportive evidence is lacking.http://dx.doi.org/10.1155/1990/728604 |
| spellingShingle | MJS Langman The Assessment of Evidence Associating Nonsteroidal Anti-Inflammatory Drugs with Complications of Peptic Ulcerations Canadian Journal of Gastroenterology |
| title | The Assessment of Evidence Associating Nonsteroidal Anti-Inflammatory Drugs with Complications of Peptic Ulcerations |
| title_full | The Assessment of Evidence Associating Nonsteroidal Anti-Inflammatory Drugs with Complications of Peptic Ulcerations |
| title_fullStr | The Assessment of Evidence Associating Nonsteroidal Anti-Inflammatory Drugs with Complications of Peptic Ulcerations |
| title_full_unstemmed | The Assessment of Evidence Associating Nonsteroidal Anti-Inflammatory Drugs with Complications of Peptic Ulcerations |
| title_short | The Assessment of Evidence Associating Nonsteroidal Anti-Inflammatory Drugs with Complications of Peptic Ulcerations |
| title_sort | assessment of evidence associating nonsteroidal anti inflammatory drugs with complications of peptic ulcerations |
| url | http://dx.doi.org/10.1155/1990/728604 |
| work_keys_str_mv | AT mjslangman theassessmentofevidenceassociatingnonsteroidalantiinflammatorydrugswithcomplicationsofpepticulcerations AT mjslangman assessmentofevidenceassociatingnonsteroidalantiinflammatorydrugswithcomplicationsofpepticulcerations |