Innovative approaches to CAR-T cell therapy: the role of lipid metabolism pathways

Abstract The efficient response structure of chimeric antigen receptor T (CAR-T) cells has led to significant success in the treatment of hematological malignancies. However, when confronted with the challenges associated with solid tumors, CAR-T cells have increasingly exhibited limitations, includ...

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Bibliographic Details
Main Authors: Minjie Guo, Yuting Zhang, Xiao Yuan, Xu Wang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06718-6
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