Endometrioid adenocarcinoma of the colon arising from rare malignant transformation of extra-gonadal endometrioma
Background: Endometriosis is a common condition with a rare malignant potential. We report a case of a patient with a colon mass who underwent surgery for malignant endometriosis associated cancer.Case: A 70-year-old woman with a pelvic mass who was lost to follow-up for 6 years represented with an...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Gynecologic Oncology Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352578924002431 |
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| author | Anne Stoklosa Youngeun Armbuster Lila Marshall Jamie L McDowell Naixin Zhang Ashlee Smith Cynthia Angel Aaron Varghese Wei Huang Richard Moore |
| author_facet | Anne Stoklosa Youngeun Armbuster Lila Marshall Jamie L McDowell Naixin Zhang Ashlee Smith Cynthia Angel Aaron Varghese Wei Huang Richard Moore |
| author_sort | Anne Stoklosa |
| collection | DOAJ |
| description | Background: Endometriosis is a common condition with a rare malignant potential. We report a case of a patient with a colon mass who underwent surgery for malignant endometriosis associated cancer.Case: A 70-year-old woman with a pelvic mass who was lost to follow-up for 6 years represented with an enlarging pelvic mass involving the sigmoid colon. The patient underwent colonoscopy which revealed atypical endometrial-type glandular proliferation. She then underwent exploratory laparotomy with total abdominal hysterectomy, bilateral salpingo-oophorectomy, rectosigmoid resection, and creation of end colostomy. Final pathology revealed endometrioid adenocarcinoma arising from colon serosal endometriosis. Observation or systemic chemotherapy were considered, and patient opted for observation. Conclusion: We report a case of malignant intestinal endometriosis. There is limited evidence to support a standardized approach to treatment due to the rare nature of this disease; the patient opted for observation. By understanding the presentation, diagnostic workup, and outcomes of each patient with malignant endometriosis, future research can be guided to ultimately improve patient outcomes. |
| format | Article |
| id | doaj-art-5db6badc770d41c183162edc5bbd29c2 |
| institution | DOAJ |
| issn | 2352-5789 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Gynecologic Oncology Reports |
| spelling | doaj-art-5db6badc770d41c183162edc5bbd29c22025-08-20T02:43:29ZengElsevierGynecologic Oncology Reports2352-57892025-02-015710166410.1016/j.gore.2024.101664Endometrioid adenocarcinoma of the colon arising from rare malignant transformation of extra-gonadal endometriomaAnne Stoklosa0Youngeun Armbuster1Lila Marshall2Jamie L McDowell3Naixin Zhang4Ashlee Smith5Cynthia Angel6Aaron Varghese7Wei Huang8Richard Moore9Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USADepartment of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USADepartment of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USADivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USADivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USA; Corresponding author at: University of Rochester Medical Center, 601 Elmwood Ave, Rochester, NY 14642, USA.Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USADivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USADivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USADepartment of Pathology, University of Rochester Medical Center, Rochester, NY, USADivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USABackground: Endometriosis is a common condition with a rare malignant potential. We report a case of a patient with a colon mass who underwent surgery for malignant endometriosis associated cancer.Case: A 70-year-old woman with a pelvic mass who was lost to follow-up for 6 years represented with an enlarging pelvic mass involving the sigmoid colon. The patient underwent colonoscopy which revealed atypical endometrial-type glandular proliferation. She then underwent exploratory laparotomy with total abdominal hysterectomy, bilateral salpingo-oophorectomy, rectosigmoid resection, and creation of end colostomy. Final pathology revealed endometrioid adenocarcinoma arising from colon serosal endometriosis. Observation or systemic chemotherapy were considered, and patient opted for observation. Conclusion: We report a case of malignant intestinal endometriosis. There is limited evidence to support a standardized approach to treatment due to the rare nature of this disease; the patient opted for observation. By understanding the presentation, diagnostic workup, and outcomes of each patient with malignant endometriosis, future research can be guided to ultimately improve patient outcomes.http://www.sciencedirect.com/science/article/pii/S2352578924002431 |
| spellingShingle | Anne Stoklosa Youngeun Armbuster Lila Marshall Jamie L McDowell Naixin Zhang Ashlee Smith Cynthia Angel Aaron Varghese Wei Huang Richard Moore Endometrioid adenocarcinoma of the colon arising from rare malignant transformation of extra-gonadal endometrioma Gynecologic Oncology Reports |
| title | Endometrioid adenocarcinoma of the colon arising from rare malignant transformation of extra-gonadal endometrioma |
| title_full | Endometrioid adenocarcinoma of the colon arising from rare malignant transformation of extra-gonadal endometrioma |
| title_fullStr | Endometrioid adenocarcinoma of the colon arising from rare malignant transformation of extra-gonadal endometrioma |
| title_full_unstemmed | Endometrioid adenocarcinoma of the colon arising from rare malignant transformation of extra-gonadal endometrioma |
| title_short | Endometrioid adenocarcinoma of the colon arising from rare malignant transformation of extra-gonadal endometrioma |
| title_sort | endometrioid adenocarcinoma of the colon arising from rare malignant transformation of extra gonadal endometrioma |
| url | http://www.sciencedirect.com/science/article/pii/S2352578924002431 |
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