Two-Dimensional NMR Spectroscopy: A Powerful Tool for the Investigation of Molecular Structure and Dynamics

Today chemical research is hardly conceivable without nuclear magnetic resonance. It has proved to be an exceedingly rich source of information for exploring the structure of molecules in solution, for the investigation of solid materials, and for the study of molecular dynamics. In order to cope w...

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Main Author: Richard R. Ernst
Format: Article
Language:deu
Published: Swiss Chemical Society 1987-10-01
Series:CHIMIA
Online Access:https://www.chimia.ch/chimia/article/view/9808
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author Richard R. Ernst
author_facet Richard R. Ernst
author_sort Richard R. Ernst
collection DOAJ
description Today chemical research is hardly conceivable without nuclear magnetic resonance. It has proved to be an exceedingly rich source of information for exploring the structure of molecules in solution, for the investigation of solid materials, and for the study of molecular dynamics. In order to cope with the overwhelming information content, an extension to two-dimensional spectroscopy turned out to be indispensibel. Two-dimensional spectroscopy has contributed, since its introduction twelve years ago, a large number of new powerful techniques for the elucidation of coupling networks by 2D correlation spectroscopy, for the measurement of internuclear distances by 2D cross-relaxation spectroscopy, and for the investigation of chemical exchange networks by 2D exchange spectroscopy. These new techniques are particularly useful for the analysis of large molecules in chemistry and in biology.
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spelling doaj-art-5db3ef2cf99645558b6451be7312c2202025-08-20T02:20:26ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24241987-10-01411010.2533/chimia.1987.323Two-Dimensional NMR Spectroscopy: A Powerful Tool for the Investigation of Molecular Structure and DynamicsRichard R. Ernst0Laboratorium für Physikalische Chemie Eidgenössische Technische Hochschule Zürich ETH-Zentrum, Universitätstrasse 22 CH-8092 Zürich Today chemical research is hardly conceivable without nuclear magnetic resonance. It has proved to be an exceedingly rich source of information for exploring the structure of molecules in solution, for the investigation of solid materials, and for the study of molecular dynamics. In order to cope with the overwhelming information content, an extension to two-dimensional spectroscopy turned out to be indispensibel. Two-dimensional spectroscopy has contributed, since its introduction twelve years ago, a large number of new powerful techniques for the elucidation of coupling networks by 2D correlation spectroscopy, for the measurement of internuclear distances by 2D cross-relaxation spectroscopy, and for the investigation of chemical exchange networks by 2D exchange spectroscopy. These new techniques are particularly useful for the analysis of large molecules in chemistry and in biology. https://www.chimia.ch/chimia/article/view/9808
spellingShingle Richard R. Ernst
Two-Dimensional NMR Spectroscopy: A Powerful Tool for the Investigation of Molecular Structure and Dynamics
CHIMIA
title Two-Dimensional NMR Spectroscopy: A Powerful Tool for the Investigation of Molecular Structure and Dynamics
title_full Two-Dimensional NMR Spectroscopy: A Powerful Tool for the Investigation of Molecular Structure and Dynamics
title_fullStr Two-Dimensional NMR Spectroscopy: A Powerful Tool for the Investigation of Molecular Structure and Dynamics
title_full_unstemmed Two-Dimensional NMR Spectroscopy: A Powerful Tool for the Investigation of Molecular Structure and Dynamics
title_short Two-Dimensional NMR Spectroscopy: A Powerful Tool for the Investigation of Molecular Structure and Dynamics
title_sort two dimensional nmr spectroscopy a powerful tool for the investigation of molecular structure and dynamics
url https://www.chimia.ch/chimia/article/view/9808
work_keys_str_mv AT richardrernst twodimensionalnmrspectroscopyapowerfultoolfortheinvestigationofmolecularstructureanddynamics