Cellular rejection of pancreaticoduodenal graft

Aim. The evaluation of donor’s duodenum histological examination in diagnosis of pancreaticoduodenal graft rejection.Materials and methods. The 35-yo patient with terminal diabetic nephropathy undergone simultaneous retroperitoneal kidney and pancreas transplantation  with enteric exocrine drainage...

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Main Authors: A. V. Pinchuk, R. V. Storozhev, I. V. Dmitriev, N. V. Shmarina, G. A. Nefedova, R. Sh. Muslimov, Yu. S. Teterin
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2018-09-01
Series:Вестник трансплантологии и искусственных органов
Subjects:
Online Access:https://journal.transpl.ru/vtio/article/view/916
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author A. V. Pinchuk
R. V. Storozhev
I. V. Dmitriev
N. V. Shmarina
G. A. Nefedova
R. Sh. Muslimov
Yu. S. Teterin
author_facet A. V. Pinchuk
R. V. Storozhev
I. V. Dmitriev
N. V. Shmarina
G. A. Nefedova
R. Sh. Muslimov
Yu. S. Teterin
author_sort A. V. Pinchuk
collection DOAJ
description Aim. The evaluation of donor’s duodenum histological examination in diagnosis of pancreaticoduodenal graft rejection.Materials and methods. The 35-yo patient with terminal diabetic nephropathy undergone simultaneous retroperitoneal kidney and pancreas transplantation  with enteric exocrine drainage of the graft via inter-duodenal anastomosis. When performing the esophagogastroduodenoscopy 2 years posttransplant we  implemented histologic examination of the duodenum of the graft.Results. We diagnosed and verified severe cellular rejection of pancreaticoduodenal graft. Successful etiopathogenetic treatment of acute  rejection of the graft (pulse therapy with glucocorticoids) was performed.Discussion. The diagnostic value of donor’s duodenum morphological examination in the diagnosis of pancreaticoduodenal graft  rejection, the efficacy of anti-rejection treatment were performed in this case.
format Article
id doaj-art-5db31ad0611447e9b51f3d7f7c2e1abe
institution DOAJ
issn 1995-1191
language Russian
publishDate 2018-09-01
publisher Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
record_format Article
series Вестник трансплантологии и искусственных органов
spelling doaj-art-5db31ad0611447e9b51f3d7f7c2e1abe2025-08-20T03:01:38ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912018-09-01203808610.15825/1995-1191-2018-3-80-86725Cellular rejection of pancreaticoduodenal graftA. V. Pinchuk0R. V. Storozhev1I. V. Dmitriev2N. V. Shmarina3G. A. Nefedova4R. Sh. Muslimov5Yu. S. Teterin6N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare DepartmentN.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare DepartmentN.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare DepartmentN.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare DepartmentN.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare DepartmentN.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare DepartmentN.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Healthcare DepartmentAim. The evaluation of donor’s duodenum histological examination in diagnosis of pancreaticoduodenal graft rejection.Materials and methods. The 35-yo patient with terminal diabetic nephropathy undergone simultaneous retroperitoneal kidney and pancreas transplantation  with enteric exocrine drainage of the graft via inter-duodenal anastomosis. When performing the esophagogastroduodenoscopy 2 years posttransplant we  implemented histologic examination of the duodenum of the graft.Results. We diagnosed and verified severe cellular rejection of pancreaticoduodenal graft. Successful etiopathogenetic treatment of acute  rejection of the graft (pulse therapy with glucocorticoids) was performed.Discussion. The diagnostic value of donor’s duodenum morphological examination in the diagnosis of pancreaticoduodenal graft  rejection, the efficacy of anti-rejection treatment were performed in this case.https://journal.transpl.ru/vtio/article/view/916pancreas transplantationdiagnosis of acute rejectionpancreaticoduodenal graft biopsy
spellingShingle A. V. Pinchuk
R. V. Storozhev
I. V. Dmitriev
N. V. Shmarina
G. A. Nefedova
R. Sh. Muslimov
Yu. S. Teterin
Cellular rejection of pancreaticoduodenal graft
Вестник трансплантологии и искусственных органов
pancreas transplantation
diagnosis of acute rejection
pancreaticoduodenal graft biopsy
title Cellular rejection of pancreaticoduodenal graft
title_full Cellular rejection of pancreaticoduodenal graft
title_fullStr Cellular rejection of pancreaticoduodenal graft
title_full_unstemmed Cellular rejection of pancreaticoduodenal graft
title_short Cellular rejection of pancreaticoduodenal graft
title_sort cellular rejection of pancreaticoduodenal graft
topic pancreas transplantation
diagnosis of acute rejection
pancreaticoduodenal graft biopsy
url https://journal.transpl.ru/vtio/article/view/916
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AT nvshmarina cellularrejectionofpancreaticoduodenalgraft
AT ganefedova cellularrejectionofpancreaticoduodenalgraft
AT rshmuslimov cellularrejectionofpancreaticoduodenalgraft
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