Metabolic profiling of lung cancer cells with acquired resistance to sotorasib

Objective·To explore the metabolic profiling and metabolic reprogramming patterns of lung cancer cells with acquired resistance to sotorasib, a specific inhibitor to KRAS.Methods·The H2122 and H358 lung cancer cell models with acquired resistance to sotorasib (H2122-SR and H358-SR cells) were establ...

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Bibliographic Details
Main Authors: ZOU Peichen, LIU Hongyu, AIHEMAITI· Ayinazhaer, ZHU Liang, TANG Yabin, LEI Huimin
Format: Article
Language:zho
Published: Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) 2025-02-01
Series:Shanghai Jiaotong Daxue xuebao. Yixue ban
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Online Access:https://xuebao.shsmu.edu.cn/CN/10.3969/j.issn.1674-8115.2025.02.002
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