Thrombocytopenia in Plasmodium vivax Malaria: How Significant?

Introduction. Thrombocytopenia is frequently noticed with P. falciparum malaria but is less reported and studied with P. vivax. Materials and Methods. The study was conducted in the Department of Medicine, SBKS MI & RC, Pipariya. We included patients who were diagnosed with vivax malaria. The da...

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Main Authors: Arti Muley, Jitendra Lakhani, Saurabh Bhirud, Abhinam Patel
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Tropical Medicine
Online Access:http://dx.doi.org/10.1155/2014/567469
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author Arti Muley
Jitendra Lakhani
Saurabh Bhirud
Abhinam Patel
author_facet Arti Muley
Jitendra Lakhani
Saurabh Bhirud
Abhinam Patel
author_sort Arti Muley
collection DOAJ
description Introduction. Thrombocytopenia is frequently noticed with P. falciparum malaria but is less reported and studied with P. vivax. Materials and Methods. The study was conducted in the Department of Medicine, SBKS MI & RC, Pipariya. We included patients who were diagnosed with vivax malaria. The data regarding their clinical and hematological profile was collected and analysed. Result. A total of 66 patients were included. 42 (63%) had platelet count <100000/mm3. Mean platelet count was 1,18,650, range being 8000/mm3–6,10,000/mm3. Amongst those with thrombocytopenia, 16 (38.09%) had anemia, 14 (33.33%) had serum creatinine >1.2 gm/dL, 15 (35.71%) had jaundice (s. bilirubin > 1.2), 2 (4.76%) had altered sensorium, 6 (14.28%) had ARDS, 2 needed ventilator support, and 1 expired. Amongst those with normal platelet count, 5 (20.83%) had anemia and 1 had jaundice whereas none had elevated s. creatinine, altered sensorium, or lung involvement. Conclusion. Thrombocytopenia is now being seen more commonly with vivax malaria. Patients with platelet count <1 lac/cumm have more severe disease.
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institution Kabale University
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spelling doaj-art-5d9a853e28f8481fa12d8dcc0978de8b2025-02-03T06:01:09ZengWileyJournal of Tropical Medicine1687-96861687-96942014-01-01201410.1155/2014/567469567469Thrombocytopenia in Plasmodium vivax Malaria: How Significant?Arti Muley0Jitendra Lakhani1Saurabh Bhirud2Abhinam Patel3SBKS MI & RC, Sumandeep Vidyapeeth, Piparia, Vadodara 390024, IndiaSBKS MI & RC, Sumandeep Vidyapeeth, Piparia, Vadodara 390024, IndiaSBKS MI & RC, Sumandeep Vidyapeeth, Piparia, Vadodara 390024, IndiaSBKS MI & RC, Sumandeep Vidyapeeth, Piparia, Vadodara 390024, IndiaIntroduction. Thrombocytopenia is frequently noticed with P. falciparum malaria but is less reported and studied with P. vivax. Materials and Methods. The study was conducted in the Department of Medicine, SBKS MI & RC, Pipariya. We included patients who were diagnosed with vivax malaria. The data regarding their clinical and hematological profile was collected and analysed. Result. A total of 66 patients were included. 42 (63%) had platelet count <100000/mm3. Mean platelet count was 1,18,650, range being 8000/mm3–6,10,000/mm3. Amongst those with thrombocytopenia, 16 (38.09%) had anemia, 14 (33.33%) had serum creatinine >1.2 gm/dL, 15 (35.71%) had jaundice (s. bilirubin > 1.2), 2 (4.76%) had altered sensorium, 6 (14.28%) had ARDS, 2 needed ventilator support, and 1 expired. Amongst those with normal platelet count, 5 (20.83%) had anemia and 1 had jaundice whereas none had elevated s. creatinine, altered sensorium, or lung involvement. Conclusion. Thrombocytopenia is now being seen more commonly with vivax malaria. Patients with platelet count <1 lac/cumm have more severe disease.http://dx.doi.org/10.1155/2014/567469
spellingShingle Arti Muley
Jitendra Lakhani
Saurabh Bhirud
Abhinam Patel
Thrombocytopenia in Plasmodium vivax Malaria: How Significant?
Journal of Tropical Medicine
title Thrombocytopenia in Plasmodium vivax Malaria: How Significant?
title_full Thrombocytopenia in Plasmodium vivax Malaria: How Significant?
title_fullStr Thrombocytopenia in Plasmodium vivax Malaria: How Significant?
title_full_unstemmed Thrombocytopenia in Plasmodium vivax Malaria: How Significant?
title_short Thrombocytopenia in Plasmodium vivax Malaria: How Significant?
title_sort thrombocytopenia in plasmodium vivax malaria how significant
url http://dx.doi.org/10.1155/2014/567469
work_keys_str_mv AT artimuley thrombocytopeniainplasmodiumvivaxmalariahowsignificant
AT jitendralakhani thrombocytopeniainplasmodiumvivaxmalariahowsignificant
AT saurabhbhirud thrombocytopeniainplasmodiumvivaxmalariahowsignificant
AT abhinampatel thrombocytopeniainplasmodiumvivaxmalariahowsignificant