Validity and reliability of the Critical-Care Pain Observation Tool (CPOT) for critically ill pediatric patients.

<h4>Introduction</h4>In some regions, critically ill pediatric and adult patients are cared for in the same intensive care unit, complicating pain assessment due to mixed age groups. To address this, it is essential to use pain scales that are applicable to a wide age range. The Critical...

Full description

Saved in:
Bibliographic Details
Main Authors: Haruhiko Hoshino, Mitsuki Ikeda, Yujiro Matsuishi, Yuki Enomoto, Nobutake Shimojo, Misaki Kotani, Shunsuke Kobayashi, Takahiro Kido, Satomi Hayashi, Yoko Furuya, Yoshiaki Inoue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0320373
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850199309245480960
author Haruhiko Hoshino
Mitsuki Ikeda
Yujiro Matsuishi
Yuki Enomoto
Nobutake Shimojo
Misaki Kotani
Shunsuke Kobayashi
Takahiro Kido
Satomi Hayashi
Yoko Furuya
Yoshiaki Inoue
author_facet Haruhiko Hoshino
Mitsuki Ikeda
Yujiro Matsuishi
Yuki Enomoto
Nobutake Shimojo
Misaki Kotani
Shunsuke Kobayashi
Takahiro Kido
Satomi Hayashi
Yoko Furuya
Yoshiaki Inoue
author_sort Haruhiko Hoshino
collection DOAJ
description <h4>Introduction</h4>In some regions, critically ill pediatric and adult patients are cared for in the same intensive care unit, complicating pain assessment due to mixed age groups. To address this, it is essential to use pain scales that are applicable to a wide age range. The Critical-Care Pain Observation Tool (CPOT) was developed to assess pain in both intubated and non-intubated adult patients. However, its applicability in pediatric patients has not been confirmed. The purpose of this study was to evaluate CPOT for critically ill pediatric patients.<h4>Methods</h4>We conducted a prospective observational study in an eight-bed open PICU from January 2022 to March 2023. Three research nurses independently assessed pain using CPOT, the Face, Legs, Activity, Cry, Consolability (FLACC) scale, and an Observational Visual Analog Scale (VAS obs). Criterion-related and construct validity were examined using Spearman's rank correlation coefficients between CPOT, VAS obs, and FLACC. Diagnostic performance was evaluated via ROC analysis using a FLACC score ≥ 4 as the reference. CPOT scores with and without medical interventions were compared using the Mann-Whitney U test, and inter-rater reliability was assessed with Cohen's weighted κ.<h4>Results</h4>Ninety-one patients were observed 165 times. CPOT strongly correlated with VAS obs (Spearman's ρ =  0.87, p <  0.01) and FLACC (Spearman's ρ =  0.84, p <  0.01). At a CPOT cut-off score of 3, sensitivity was 100% and specificity was 96.7%. CPOT effectively reflected pain levels during medical interventions (p <  0.01), and inter-rater reliability was high (weighted κ =  0.89, 95% CI: 0.799-0.941).<h4>Conclusions</h4>This study suggests that CPOT may be a useful tool for pain assessment in pediatric patients.
format Article
id doaj-art-5d9965fe870546f3a61cda13fae3f0a2
institution OA Journals
issn 1932-6203
language English
publishDate 2025-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS ONE
spelling doaj-art-5d9965fe870546f3a61cda13fae3f0a22025-08-20T02:12:38ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01204e032037310.1371/journal.pone.0320373Validity and reliability of the Critical-Care Pain Observation Tool (CPOT) for critically ill pediatric patients.Haruhiko HoshinoMitsuki IkedaYujiro MatsuishiYuki EnomotoNobutake ShimojoMisaki KotaniShunsuke KobayashiTakahiro KidoSatomi HayashiYoko FuruyaYoshiaki Inoue<h4>Introduction</h4>In some regions, critically ill pediatric and adult patients are cared for in the same intensive care unit, complicating pain assessment due to mixed age groups. To address this, it is essential to use pain scales that are applicable to a wide age range. The Critical-Care Pain Observation Tool (CPOT) was developed to assess pain in both intubated and non-intubated adult patients. However, its applicability in pediatric patients has not been confirmed. The purpose of this study was to evaluate CPOT for critically ill pediatric patients.<h4>Methods</h4>We conducted a prospective observational study in an eight-bed open PICU from January 2022 to March 2023. Three research nurses independently assessed pain using CPOT, the Face, Legs, Activity, Cry, Consolability (FLACC) scale, and an Observational Visual Analog Scale (VAS obs). Criterion-related and construct validity were examined using Spearman's rank correlation coefficients between CPOT, VAS obs, and FLACC. Diagnostic performance was evaluated via ROC analysis using a FLACC score ≥ 4 as the reference. CPOT scores with and without medical interventions were compared using the Mann-Whitney U test, and inter-rater reliability was assessed with Cohen's weighted κ.<h4>Results</h4>Ninety-one patients were observed 165 times. CPOT strongly correlated with VAS obs (Spearman's ρ =  0.87, p <  0.01) and FLACC (Spearman's ρ =  0.84, p <  0.01). At a CPOT cut-off score of 3, sensitivity was 100% and specificity was 96.7%. CPOT effectively reflected pain levels during medical interventions (p <  0.01), and inter-rater reliability was high (weighted κ =  0.89, 95% CI: 0.799-0.941).<h4>Conclusions</h4>This study suggests that CPOT may be a useful tool for pain assessment in pediatric patients.https://doi.org/10.1371/journal.pone.0320373
spellingShingle Haruhiko Hoshino
Mitsuki Ikeda
Yujiro Matsuishi
Yuki Enomoto
Nobutake Shimojo
Misaki Kotani
Shunsuke Kobayashi
Takahiro Kido
Satomi Hayashi
Yoko Furuya
Yoshiaki Inoue
Validity and reliability of the Critical-Care Pain Observation Tool (CPOT) for critically ill pediatric patients.
PLoS ONE
title Validity and reliability of the Critical-Care Pain Observation Tool (CPOT) for critically ill pediatric patients.
title_full Validity and reliability of the Critical-Care Pain Observation Tool (CPOT) for critically ill pediatric patients.
title_fullStr Validity and reliability of the Critical-Care Pain Observation Tool (CPOT) for critically ill pediatric patients.
title_full_unstemmed Validity and reliability of the Critical-Care Pain Observation Tool (CPOT) for critically ill pediatric patients.
title_short Validity and reliability of the Critical-Care Pain Observation Tool (CPOT) for critically ill pediatric patients.
title_sort validity and reliability of the critical care pain observation tool cpot for critically ill pediatric patients
url https://doi.org/10.1371/journal.pone.0320373
work_keys_str_mv AT haruhikohoshino validityandreliabilityofthecriticalcarepainobservationtoolcpotforcriticallyillpediatricpatients
AT mitsukiikeda validityandreliabilityofthecriticalcarepainobservationtoolcpotforcriticallyillpediatricpatients
AT yujiromatsuishi validityandreliabilityofthecriticalcarepainobservationtoolcpotforcriticallyillpediatricpatients
AT yukienomoto validityandreliabilityofthecriticalcarepainobservationtoolcpotforcriticallyillpediatricpatients
AT nobutakeshimojo validityandreliabilityofthecriticalcarepainobservationtoolcpotforcriticallyillpediatricpatients
AT misakikotani validityandreliabilityofthecriticalcarepainobservationtoolcpotforcriticallyillpediatricpatients
AT shunsukekobayashi validityandreliabilityofthecriticalcarepainobservationtoolcpotforcriticallyillpediatricpatients
AT takahirokido validityandreliabilityofthecriticalcarepainobservationtoolcpotforcriticallyillpediatricpatients
AT satomihayashi validityandreliabilityofthecriticalcarepainobservationtoolcpotforcriticallyillpediatricpatients
AT yokofuruya validityandreliabilityofthecriticalcarepainobservationtoolcpotforcriticallyillpediatricpatients
AT yoshiakiinoue validityandreliabilityofthecriticalcarepainobservationtoolcpotforcriticallyillpediatricpatients