Practical Recommendation of the Scientific Сommunity for Human Microbiome Research (CHMR) and the Russian Gastroenterological Association (RGA) on Small Intestinal Bacterial Overgrowth in Adults

Aim. To optimize the choice of treatment strategies by physicians and gastroenterologists to improve treatment and prevention of small intestinal bacterial overgrowth (SIBO) in adults.Key points. SIBO is a condition characterized by an increased amount and/or abnormal composition of the microbiota i...

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Main Authors: V. T. Ivashkin, I. V. Maev, D. I. Abdulganieva, O. P. Alekseeva, S. A. Alekseenko, O. Yu. Zolnikova, N. V. Korochanskaya, O. S. Medvedev, E. A. Poluektova, V. I. Simanenkov, A. S. Trukhmanov, I. B. Khlynov, V. V. Tsukanov, O. S. Shifrin, K. V. Ivashkin, T. L. Lapina, R. V. Maslennikov, M. V. Fadeeva, A. I. Ulyanin
Format: Article
Language:Russian
Published: Gastro LLC 2022-09-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/741
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author V. T. Ivashkin
I. V. Maev
D. I. Abdulganieva
O. P. Alekseeva
S. A. Alekseenko
O. Yu. Zolnikova
N. V. Korochanskaya
O. S. Medvedev
E. A. Poluektova
V. I. Simanenkov
A. S. Trukhmanov
I. B. Khlynov
V. V. Tsukanov
O. S. Shifrin
K. V. Ivashkin
T. L. Lapina
R. V. Maslennikov
M. V. Fadeeva
A. I. Ulyanin
author_facet V. T. Ivashkin
I. V. Maev
D. I. Abdulganieva
O. P. Alekseeva
S. A. Alekseenko
O. Yu. Zolnikova
N. V. Korochanskaya
O. S. Medvedev
E. A. Poluektova
V. I. Simanenkov
A. S. Trukhmanov
I. B. Khlynov
V. V. Tsukanov
O. S. Shifrin
K. V. Ivashkin
T. L. Lapina
R. V. Maslennikov
M. V. Fadeeva
A. I. Ulyanin
author_sort V. T. Ivashkin
collection DOAJ
description Aim. To optimize the choice of treatment strategies by physicians and gastroenterologists to improve treatment and prevention of small intestinal bacterial overgrowth (SIBO) in adults.Key points. SIBO is a condition characterized by an increased amount and/or abnormal composition of the microbiota in the small intestine. Clinically, the syndrome is manifested by nonspecific gastroenterological complaints and the development of malabsorption syndrome. Most often, SIBO is associated with various chronic non- infectious diseases (both diseases of the gastrointestinal tract, and the cardiovascular system and the neuromuscular apparatus) and can affect the severity of their symptoms. Specific methods for diagnosing SIBO are the culture method and breath tests. The main approaches to the treatment of SIBO include the elimination of the underlying cause of its occurrence, the use of antibacterial drugs and adherence to dietary recommendations (elemental diet).Conclusion. Small intestinal bacterial overgrowth is common in patients with various diseases, but has non-specific manifestations, so proper diagnosis of this condition is required. SIBO therapy involves prescription of antibacterial agents, the most studied of which is the non-absorbable antibiotic rifaximin-α.
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spelling doaj-art-5d8e9adc8e50410cbf9210aae9b03f9f2025-02-10T16:14:37ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732022-09-01323688510.22416/1382-4376-2022-32-3-68-85482Practical Recommendation of the Scientific Сommunity for Human Microbiome Research (CHMR) and the Russian Gastroenterological Association (RGA) on Small Intestinal Bacterial Overgrowth in AdultsV. T. Ivashkin0I. V. Maev1D. I. Abdulganieva2O. P. Alekseeva3S. A. Alekseenko4O. Yu. Zolnikova5N. V. Korochanskaya6O. S. Medvedev7E. A. Poluektova8V. I. Simanenkov9A. S. Trukhmanov10I. B. Khlynov11V. V. Tsukanov12O. S. Shifrin13K. V. Ivashkin14T. L. Lapina15R. V. Maslennikov16M. V. Fadeeva17A. I. Ulyanin18I.M. Sechenov First Moscow State Medical University (Sechenov University)Yevdokimov Moscow State University of Medicine and DentistryKazan State Medical UniversityPrivolzhsky Research Medical UniversityFar-Eastern State Medical UniversityI.M. Sechenov First Moscow State Medical University (Sechenov University)Kuban State Medical UniversityLomonosov Moscow State University; Institute of Experimental Cardiology of National Medical Research Center of CardiologyI.M. Sechenov First Moscow State Medical University (Sechenov University)Mechnikov North-West State Medical UniversityI.M. Sechenov First Moscow State Medical University (Sechenov University)Ural State Medical UniversityResearch Institute for Medical Problems in the North — Division of Krasnoyarsk Scientific Centre of the Siberian Branch of the RASI.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)Aim. To optimize the choice of treatment strategies by physicians and gastroenterologists to improve treatment and prevention of small intestinal bacterial overgrowth (SIBO) in adults.Key points. SIBO is a condition characterized by an increased amount and/or abnormal composition of the microbiota in the small intestine. Clinically, the syndrome is manifested by nonspecific gastroenterological complaints and the development of malabsorption syndrome. Most often, SIBO is associated with various chronic non- infectious diseases (both diseases of the gastrointestinal tract, and the cardiovascular system and the neuromuscular apparatus) and can affect the severity of their symptoms. Specific methods for diagnosing SIBO are the culture method and breath tests. The main approaches to the treatment of SIBO include the elimination of the underlying cause of its occurrence, the use of antibacterial drugs and adherence to dietary recommendations (elemental diet).Conclusion. Small intestinal bacterial overgrowth is common in patients with various diseases, but has non-specific manifestations, so proper diagnosis of this condition is required. SIBO therapy involves prescription of antibacterial agents, the most studied of which is the non-absorbable antibiotic rifaximin-α.https://www.gastro-j.ru/jour/article/view/741small intestinal bacterial overgrowthmicrobiotabreath testingrifaximin-α
spellingShingle V. T. Ivashkin
I. V. Maev
D. I. Abdulganieva
O. P. Alekseeva
S. A. Alekseenko
O. Yu. Zolnikova
N. V. Korochanskaya
O. S. Medvedev
E. A. Poluektova
V. I. Simanenkov
A. S. Trukhmanov
I. B. Khlynov
V. V. Tsukanov
O. S. Shifrin
K. V. Ivashkin
T. L. Lapina
R. V. Maslennikov
M. V. Fadeeva
A. I. Ulyanin
Practical Recommendation of the Scientific Сommunity for Human Microbiome Research (CHMR) and the Russian Gastroenterological Association (RGA) on Small Intestinal Bacterial Overgrowth in Adults
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
small intestinal bacterial overgrowth
microbiota
breath testing
rifaximin-α
title Practical Recommendation of the Scientific Сommunity for Human Microbiome Research (CHMR) and the Russian Gastroenterological Association (RGA) on Small Intestinal Bacterial Overgrowth in Adults
title_full Practical Recommendation of the Scientific Сommunity for Human Microbiome Research (CHMR) and the Russian Gastroenterological Association (RGA) on Small Intestinal Bacterial Overgrowth in Adults
title_fullStr Practical Recommendation of the Scientific Сommunity for Human Microbiome Research (CHMR) and the Russian Gastroenterological Association (RGA) on Small Intestinal Bacterial Overgrowth in Adults
title_full_unstemmed Practical Recommendation of the Scientific Сommunity for Human Microbiome Research (CHMR) and the Russian Gastroenterological Association (RGA) on Small Intestinal Bacterial Overgrowth in Adults
title_short Practical Recommendation of the Scientific Сommunity for Human Microbiome Research (CHMR) and the Russian Gastroenterological Association (RGA) on Small Intestinal Bacterial Overgrowth in Adults
title_sort practical recommendation of the scientific сommunity for human microbiome research chmr and the russian gastroenterological association rga on small intestinal bacterial overgrowth in adults
topic small intestinal bacterial overgrowth
microbiota
breath testing
rifaximin-α
url https://www.gastro-j.ru/jour/article/view/741
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