Estrogen and viral infection
Gender differences exist in the susceptibility, incidence, progression, and prognosis of diseases caused by viral infections. These differences are influenced by various factors, including lifestyle and habits between males and females. Some reports have pointed out that estrogen plays an important...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-05-01
|
| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1556728/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850272616262139904 |
|---|---|
| author | Xiangrui Wei Longyan Hong Longyan Hong Hao Liang Ke Ren Wenqing Man Yinghui Zhao Yinghui Zhao Pengbo Guo Pengbo Guo |
| author_facet | Xiangrui Wei Longyan Hong Longyan Hong Hao Liang Ke Ren Wenqing Man Yinghui Zhao Yinghui Zhao Pengbo Guo Pengbo Guo |
| author_sort | Xiangrui Wei |
| collection | DOAJ |
| description | Gender differences exist in the susceptibility, incidence, progression, and prognosis of diseases caused by viral infections. These differences are influenced by various factors, including lifestyle and habits between males and females. Some reports have pointed out that estrogen plays an important immune-modulatory role in many viral infections. In certain viral infections, estrogen exhibits a protective and regulatory effect, while in others, it has a synergistic and promoting effect. The action of estrogen and its receptors affect the occurrence and prognosis of viral infections to some extent. This article reviews the correlation and the related mechanisms between estrogen and viral infections. |
| format | Article |
| id | doaj-art-5d887f85f6b346cca22cdfe5b8d8b4a2 |
| institution | OA Journals |
| issn | 1664-3224 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj-art-5d887f85f6b346cca22cdfe5b8d8b4a22025-08-20T01:51:44ZengFrontiers Media S.A.Frontiers in Immunology1664-32242025-05-011610.3389/fimmu.2025.15567281556728Estrogen and viral infectionXiangrui Wei0Longyan Hong1Longyan Hong2Hao Liang3Ke Ren4Wenqing Man5Yinghui Zhao6Yinghui Zhao7Pengbo Guo8Pengbo Guo9Department of Health Inspection and Quarantine, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, ChinaDepartment of Clinical Laboratory Medicine, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Medicine and Health Key Laboratory of Laboratory Medicine, Jinan, Shandong, ChinaDepartment of Pathogen Biology, School of Clinical and Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, ChinaDepartment of Health Inspection and Quarantine, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, ChinaDepartment of Pathogen Biology, School of Clinical and Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, ChinaSchool of Stomatology, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, ChinaDepartment of Clinical Laboratory Medicine, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Medicine and Health Key Laboratory of Laboratory Medicine, Jinan, Shandong, ChinaDepartment of Pathogen Biology, School of Clinical and Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, ChinaDepartment of Clinical Laboratory Medicine, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Medicine and Health Key Laboratory of Laboratory Medicine, Jinan, Shandong, ChinaDepartment of Pathogen Biology, School of Clinical and Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, ChinaGender differences exist in the susceptibility, incidence, progression, and prognosis of diseases caused by viral infections. These differences are influenced by various factors, including lifestyle and habits between males and females. Some reports have pointed out that estrogen plays an important immune-modulatory role in many viral infections. In certain viral infections, estrogen exhibits a protective and regulatory effect, while in others, it has a synergistic and promoting effect. The action of estrogen and its receptors affect the occurrence and prognosis of viral infections to some extent. This article reviews the correlation and the related mechanisms between estrogen and viral infections.https://www.frontiersin.org/articles/10.3389/fimmu.2025.1556728/fullestrogengender differenceimmune responseviral infectionmolecular mechanism |
| spellingShingle | Xiangrui Wei Longyan Hong Longyan Hong Hao Liang Ke Ren Wenqing Man Yinghui Zhao Yinghui Zhao Pengbo Guo Pengbo Guo Estrogen and viral infection Frontiers in Immunology estrogen gender difference immune response viral infection molecular mechanism |
| title | Estrogen and viral infection |
| title_full | Estrogen and viral infection |
| title_fullStr | Estrogen and viral infection |
| title_full_unstemmed | Estrogen and viral infection |
| title_short | Estrogen and viral infection |
| title_sort | estrogen and viral infection |
| topic | estrogen gender difference immune response viral infection molecular mechanism |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1556728/full |
| work_keys_str_mv | AT xiangruiwei estrogenandviralinfection AT longyanhong estrogenandviralinfection AT longyanhong estrogenandviralinfection AT haoliang estrogenandviralinfection AT keren estrogenandviralinfection AT wenqingman estrogenandviralinfection AT yinghuizhao estrogenandviralinfection AT yinghuizhao estrogenandviralinfection AT pengboguo estrogenandviralinfection AT pengboguo estrogenandviralinfection |