Familial hemophagocytic lymphohistiocytosis in an infant: A case report
Familial Hemophagocytic Lymphohistiocytosis (FHL) is a rare disorder of early childhood more prevalent in consanguineous families. We discuss a case of a 6-month-old female infant presenting with persistent fever, failure to thrive and neurological manifestations. Diagnosis of FHL type 2 was made ba...
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| Format: | Article |
| Language: | English |
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Krishna Vishwa Vidyapeeth (Deemed to be University), Karad
2025-01-01
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| Series: | Journal of Krishna Institute of Medical Sciences University |
| Subjects: | |
| Online Access: | https://www.jkimsu.com/jkimsu-vol14no1/JKIMSU,%20Vol.%2014,%20No.%201,%20January-March%202025%20Page%20170-175.pdf |
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| author | Sushma Belurkar Gaurvi Piplani Suneel C. Mundkar Sandeep Kumar BK Karen Janice Moras Rochelle Anne Pereiera |
| author_facet | Sushma Belurkar Gaurvi Piplani Suneel C. Mundkar Sandeep Kumar BK Karen Janice Moras Rochelle Anne Pereiera |
| author_sort | Sushma Belurkar |
| collection | DOAJ |
| description | Familial Hemophagocytic Lymphohistiocytosis (FHL) is a rare disorder of early childhood more prevalent in consanguineous families. We discuss a case of a 6-month-old female infant presenting with persistent fever, failure to thrive and neurological manifestations. Diagnosis of FHL type 2 was made based on clinical and laboratory parameters and confirmed with genetic testing. Child was started on intravenous corticosteroids under antibiotic coverage along with anti-epileptics and supportive care however the overall clinical condition did not improve and
after 6 days of hospital stay the parents requested discharge and was lost to follow- up. |
| format | Article |
| id | doaj-art-5d700b0ccfa94accbf374dd0debfa590 |
| institution | Kabale University |
| issn | 2231-4261 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Krishna Vishwa Vidyapeeth (Deemed to be University), Karad |
| record_format | Article |
| series | Journal of Krishna Institute of Medical Sciences University |
| spelling | doaj-art-5d700b0ccfa94accbf374dd0debfa5902025-08-25T11:51:47ZengKrishna Vishwa Vidyapeeth (Deemed to be University), KaradJournal of Krishna Institute of Medical Sciences University2231-42612025-01-01141170175Familial hemophagocytic lymphohistiocytosis in an infant: A case reportSushma Belurkar0Gaurvi Piplani1Suneel C. Mundkar2Sandeep Kumar BK3Karen Janice Moras4Rochelle Anne Pereiera5Department of Pathology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal (Karnataka), IndiaDepartment of Pathology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal (Karnataka), IndiaDepartment of Pediatrics, Kasturba Medical College, Manipal Academy of Higher Education, Manipal (Karnataka), IndiaDepartment of Pediatrics, Kasturba Medical College, Manipal Academy of Higher Education, Manipal (Karnataka), IndiaDepartment of Pediatrics, Kasturba Medical College, Manipal Academy of Higher Education, Manipal (Karnataka), IndiaDepartment of Pediatrics, Kasturba Medical College, Manipal Academy of Higher Education, Manipal (Karnataka), IndiaFamilial Hemophagocytic Lymphohistiocytosis (FHL) is a rare disorder of early childhood more prevalent in consanguineous families. We discuss a case of a 6-month-old female infant presenting with persistent fever, failure to thrive and neurological manifestations. Diagnosis of FHL type 2 was made based on clinical and laboratory parameters and confirmed with genetic testing. Child was started on intravenous corticosteroids under antibiotic coverage along with anti-epileptics and supportive care however the overall clinical condition did not improve and after 6 days of hospital stay the parents requested discharge and was lost to follow- up.https://www.jkimsu.com/jkimsu-vol14no1/JKIMSU,%20Vol.%2014,%20No.%201,%20January-March%202025%20Page%20170-175.pdfinfantfailure to thrivefamilial hemophagocytic lymphohistiocytosis |
| spellingShingle | Sushma Belurkar Gaurvi Piplani Suneel C. Mundkar Sandeep Kumar BK Karen Janice Moras Rochelle Anne Pereiera Familial hemophagocytic lymphohistiocytosis in an infant: A case report Journal of Krishna Institute of Medical Sciences University infant failure to thrive familial hemophagocytic lymphohistiocytosis |
| title | Familial hemophagocytic lymphohistiocytosis in an infant: A case report |
| title_full | Familial hemophagocytic lymphohistiocytosis in an infant: A case report |
| title_fullStr | Familial hemophagocytic lymphohistiocytosis in an infant: A case report |
| title_full_unstemmed | Familial hemophagocytic lymphohistiocytosis in an infant: A case report |
| title_short | Familial hemophagocytic lymphohistiocytosis in an infant: A case report |
| title_sort | familial hemophagocytic lymphohistiocytosis in an infant a case report |
| topic | infant failure to thrive familial hemophagocytic lymphohistiocytosis |
| url | https://www.jkimsu.com/jkimsu-vol14no1/JKIMSU,%20Vol.%2014,%20No.%201,%20January-March%202025%20Page%20170-175.pdf |
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