Maternal erythrocytosis as a risk factor for small for gestational age at term in high altitude
Abstract Objective To determine if maternal erythrocytosis is a risk factor for small-for-gestational age at term at 3,400-m altitude in pregnant women without intercurrent disease. Methods Analytical study of retrospective cohorts at Cusco, a city at 3,400-m altitude. Our participants were 224...
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Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
2025-02-01
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| Series: | Revista Brasileira de Ginecologia e Obstetrícia |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032024000100266&lng=en&tlng=en |
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| author | Wilfredo Villamonte-Calanche Marco Antonio Salazar-Zegarra Cleto De-la-Torre-Dueñas Alexandra Villamonte-Jerí Adaí Vera-Luza Milagros Hilari Bustinza-Apaza Nuria Huanca-Huirse |
| author_facet | Wilfredo Villamonte-Calanche Marco Antonio Salazar-Zegarra Cleto De-la-Torre-Dueñas Alexandra Villamonte-Jerí Adaí Vera-Luza Milagros Hilari Bustinza-Apaza Nuria Huanca-Huirse |
| author_sort | Wilfredo Villamonte-Calanche |
| collection | DOAJ |
| description | Abstract Objective To determine if maternal erythrocytosis is a risk factor for small-for-gestational age at term at 3,400-m altitude in pregnant women without intercurrent disease. Methods Analytical study of retrospective cohorts at Cusco, a city at 3,400-m altitude. Our participants were 224 and 483 pregnant women with and without exposure to maternal erythrocytosis, respectively. A logistic regression with the goodness of fit to the proposed model was also performed with the Hosmer and Lemeshow test, evaluating the small-for-gestational-age results with or without exposure to hemoglobin >14.5 g/dl. Results The incidence of small-for-gestational-age was 6.9% for this entire cohort. The maternal erythrocytosis during gestation without any maternal morbidity at 3,400-m altitude has an ORa=0.691 (p=0.271) for small-for-gestational-age at term. Inadequate prenatal control has an ORa=2.115 (p=0.016) for small-for-gestational-age compared to adequate prenatal control. Conclusion Maternal erythrocytosis in pregnant women without any morbidity is not a risk factor for small-for-gestational-age at 3,400 m-altitude. |
| format | Article |
| id | doaj-art-5d700303045a460e9ed9099c317adfc5 |
| institution | Kabale University |
| issn | 0100-7203 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Federação Brasileira das Sociedades de Ginecologia e Obstetrícia |
| record_format | Article |
| series | Revista Brasileira de Ginecologia e Obstetrícia |
| spelling | doaj-art-5d700303045a460e9ed9099c317adfc52025-02-11T07:44:21ZengFederação Brasileira das Sociedades de Ginecologia e ObstetríciaRevista Brasileira de Ginecologia e Obstetrícia0100-72032025-02-014610.61622/rbgo/2024rbgo98Maternal erythrocytosis as a risk factor for small for gestational age at term in high altitudeWilfredo Villamonte-Calanchehttps://orcid.org/0000-0001-8723-0252Marco Antonio Salazar-Zegarrahttps://orcid.org/0000-0003-2231-058XCleto De-la-Torre-Dueñashttps://orcid.org/0000-0003-0921-7217Alexandra Villamonte-Jeríhttps://orcid.org/0000-0002-5071-5106Adaí Vera-Luzahttps://orcid.org/0000-0002-8748-5033Milagros Hilari Bustinza-Apazahttps://orcid.org/0000-0001-5644-5912Nuria Huanca-Huirsehttps://orcid.org/0000-0002-9972-5727Abstract Objective To determine if maternal erythrocytosis is a risk factor for small-for-gestational age at term at 3,400-m altitude in pregnant women without intercurrent disease. Methods Analytical study of retrospective cohorts at Cusco, a city at 3,400-m altitude. Our participants were 224 and 483 pregnant women with and without exposure to maternal erythrocytosis, respectively. A logistic regression with the goodness of fit to the proposed model was also performed with the Hosmer and Lemeshow test, evaluating the small-for-gestational-age results with or without exposure to hemoglobin >14.5 g/dl. Results The incidence of small-for-gestational-age was 6.9% for this entire cohort. The maternal erythrocytosis during gestation without any maternal morbidity at 3,400-m altitude has an ORa=0.691 (p=0.271) for small-for-gestational-age at term. Inadequate prenatal control has an ORa=2.115 (p=0.016) for small-for-gestational-age compared to adequate prenatal control. Conclusion Maternal erythrocytosis in pregnant women without any morbidity is not a risk factor for small-for-gestational-age at 3,400 m-altitude.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032024000100266&lng=en&tlng=enPregnancyPregnant womenGestational agePolycythemiaAltitudeHypoxiaFetal growth retardationNeonatal mortalityMorbidityHemoglobinSmall for gestational ageRisk factors |
| spellingShingle | Wilfredo Villamonte-Calanche Marco Antonio Salazar-Zegarra Cleto De-la-Torre-Dueñas Alexandra Villamonte-Jerí Adaí Vera-Luza Milagros Hilari Bustinza-Apaza Nuria Huanca-Huirse Maternal erythrocytosis as a risk factor for small for gestational age at term in high altitude Revista Brasileira de Ginecologia e Obstetrícia Pregnancy Pregnant women Gestational age Polycythemia Altitude Hypoxia Fetal growth retardation Neonatal mortality Morbidity Hemoglobin Small for gestational age Risk factors |
| title | Maternal erythrocytosis as a risk factor for small for gestational age at term in high altitude |
| title_full | Maternal erythrocytosis as a risk factor for small for gestational age at term in high altitude |
| title_fullStr | Maternal erythrocytosis as a risk factor for small for gestational age at term in high altitude |
| title_full_unstemmed | Maternal erythrocytosis as a risk factor for small for gestational age at term in high altitude |
| title_short | Maternal erythrocytosis as a risk factor for small for gestational age at term in high altitude |
| title_sort | maternal erythrocytosis as a risk factor for small for gestational age at term in high altitude |
| topic | Pregnancy Pregnant women Gestational age Polycythemia Altitude Hypoxia Fetal growth retardation Neonatal mortality Morbidity Hemoglobin Small for gestational age Risk factors |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032024000100266&lng=en&tlng=en |
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