Ch25h and 25-HC prevent liver steatosis through regulation of cholesterol metabolism and inflammation

Ch25h and 25-HC prevent liver steatosis through regulation of cholesterol metabolism and inflammation

Non-alcoholic fatty liver disease (NAFLD) is currently the most prevalent metabolic disorder all over the world, and lipid metabolic disorders and inflammation are closely associated and contribute to the pathogenesis of NAFLD. Cholesterol 25-hydroxylase (Ch25h) and its product, 25-hydroxycholestero...

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Bibliographic Details
Main Authors: Wang Yaqiong, Zhang Jin, Chen Jie, Wang Dan, Yu Yang, Qiu Pei, Wang Qiqi, Zhao Wenbao, Li Zhao, Lei Ting
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-04-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
high fat diet
LXRα
NLRP3 inflammasome
Ch25h
25-HC
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022030
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