The role of periostin (OSF-2) in the cytoadherence phenomena mediated by malaria parasites

The role of periostin (OSF-2) in the cytoadherence phenomena mediated by malaria parasites

IntroductionThe pathogenesis of severe malaria is primarily attributed to the cytoadherence properties of Plasmodium-infected erythrocytes (IRBC), which include rosetting and IRBC-endothelial cytoadherence. These cytoadherence events are influenced by various parasite- and host-derived factors. Prev...

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Bibliographic Details
Main Authors: Zhi-Ying Phong, Joo-Yie Chin, Yee Ling Ng, Nurul Izza Zakaria, Siti Nur Athirah-Azman, Varakorn Kosaisavee, Laurent Rénia, Wenn-Chyau Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Plasmodium falciparum
Plasmodium knowlesi
OSF-2
endothelial binding
rosetting
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1599872/full
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