Copper–luteolin nanocomplexes for Mediating multifaceted regulation of oxidative stress, intestinal barrier, and gut microbiota in inflammatory bowel disease

Copper–luteolin nanocomplexes for Mediating multifaceted regulation of oxidative stress, intestinal barrier, and gut microbiota in inflammatory bowel disease

Oxidative stress, dysbiosis, and immune dysregulation have been confirmed to play pivotal roles in the complex pathogenesis of inflammatory bowel disease (IBD). Herein, we design copper ion–luteolin nanocomplexes (CuL NCs) through a metal–polyphenol coordination strategy, which plays a multifaceted...

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Bibliographic Details
Main Authors: Wanyue Fu, Zhongshi Huang, Weiqi Li, Lingling Xu, Miaomiao Yang, Yan Ma, Hanghang Liu, Haisheng Qian, Wanni Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-04-01
Series:Bioactive Materials
Subjects:
Inflammatory bowel disease
Regulating inflammatory microenvironment
Oxidative stress
Reactive oxygen species
Flora regulation
Nrf2/NF-κB
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X24005334
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