Evaluation of The Pan-Immune-Inflammation Value in Patients with Chronic Rinosinusitis
Objective: In this study, we aimed to investigate the pan-immune inflammation value (PIV) if it can predict the nasal polyp endotype of the patient without biopsy. In this regard, we aimed to obtain a new diagnostic tool that can guide the treatment of patients who do not accept biopsy or are not su...
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| Format: | Article |
| Language: | English |
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Istanbul University Press
2025-03-01
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| Series: | The Turkish Journal of Ear Nose and Throat |
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| Online Access: | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/8573754A67DC49469D5D011306774063 |
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| author | Mehmet Emre Sivrice Yusuf Tuncel Hasan Yasan Erdoğan Okur Yusuf Çağdaş Kumbul Vural Akın |
| author_facet | Mehmet Emre Sivrice Yusuf Tuncel Hasan Yasan Erdoğan Okur Yusuf Çağdaş Kumbul Vural Akın |
| author_sort | Mehmet Emre Sivrice |
| collection | DOAJ |
| description | Objective: In this study, we aimed to investigate the pan-immune inflammation value (PIV) if it can predict the nasal polyp endotype of the patient without biopsy. In this regard, we aimed to obtain a new diagnostic tool that can guide the treatment of patients who do not accept biopsy or are not suitable for surgery due to their comorbidities. Material and Methods: The study was designed as a retrospective case–control study. The study group consisted of 198 patients in the CRS group and there were 396 patients in the control group. The age, gender, grade, CBC parameters and pan-immune-inflammation value were compared statistically between the groups. Results: A statistically significant difference was observed between the control and CRS groups in terms of the PIV parameter (p<0.001). In CRS endotyping, no significant difference was observed between the type 2 and non-type 2 groups in terms of the PIV parameter (p=0.276). Conclusion: According to our results, the PIV parameter was statistically significantly higher in CRS patients than in the control group. However, it was not useful for endotyping the disease and predicting recurrence. We believe that further studies testing different inflammatory indices will be beneficial for these purposes. |
| format | Article |
| id | doaj-art-5d5cfb6ecba54e0bb6a34fbe8097e54e |
| institution | OA Journals |
| issn | 2602-4837 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Istanbul University Press |
| record_format | Article |
| series | The Turkish Journal of Ear Nose and Throat |
| spelling | doaj-art-5d5cfb6ecba54e0bb6a34fbe8097e54e2025-08-20T02:14:19ZengIstanbul University PressThe Turkish Journal of Ear Nose and Throat2602-48372025-03-01351293410.26650/Tr-ENT.2025.1466632123456Evaluation of The Pan-Immune-Inflammation Value in Patients with Chronic RinosinusitisMehmet Emre Sivrice0https://orcid.org/0000-0002-2396-6794Yusuf Tuncel1https://orcid.org/0009-0000-5552-8986Hasan Yasan2https://orcid.org/0000-0002-5470-6784Erdoğan Okur3https://orcid.org/0000-0003-4384-840XYusuf Çağdaş Kumbul4https://orcid.org/0000-0002-0713-2933Vural Akın5https://orcid.org/0000-0002-0050-4837Süleyman Demirel Üniversitesi, Isparta, TurkiyeSüleyman Demirel Üniversitesi, Isparta, TurkiyeSüleyman Demirel Üniversitesi, Isparta, TurkiyeSüleyman Demirel Üniversitesi, Isparta, TurkiyeSüleyman Demirel Üniversitesi, Isparta, TurkiyeSüleyman Demirel Üniversitesi, Isparta, TurkiyeObjective: In this study, we aimed to investigate the pan-immune inflammation value (PIV) if it can predict the nasal polyp endotype of the patient without biopsy. In this regard, we aimed to obtain a new diagnostic tool that can guide the treatment of patients who do not accept biopsy or are not suitable for surgery due to their comorbidities. Material and Methods: The study was designed as a retrospective case–control study. The study group consisted of 198 patients in the CRS group and there were 396 patients in the control group. The age, gender, grade, CBC parameters and pan-immune-inflammation value were compared statistically between the groups. Results: A statistically significant difference was observed between the control and CRS groups in terms of the PIV parameter (p<0.001). In CRS endotyping, no significant difference was observed between the type 2 and non-type 2 groups in terms of the PIV parameter (p=0.276). Conclusion: According to our results, the PIV parameter was statistically significantly higher in CRS patients than in the control group. However, it was not useful for endotyping the disease and predicting recurrence. We believe that further studies testing different inflammatory indices will be beneficial for these purposes.https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/8573754A67DC49469D5D011306774063nasal polypssinusitisinflammationindices |
| spellingShingle | Mehmet Emre Sivrice Yusuf Tuncel Hasan Yasan Erdoğan Okur Yusuf Çağdaş Kumbul Vural Akın Evaluation of The Pan-Immune-Inflammation Value in Patients with Chronic Rinosinusitis The Turkish Journal of Ear Nose and Throat nasal polyps sinusitis inflammation indices |
| title | Evaluation of The Pan-Immune-Inflammation Value in Patients with Chronic Rinosinusitis |
| title_full | Evaluation of The Pan-Immune-Inflammation Value in Patients with Chronic Rinosinusitis |
| title_fullStr | Evaluation of The Pan-Immune-Inflammation Value in Patients with Chronic Rinosinusitis |
| title_full_unstemmed | Evaluation of The Pan-Immune-Inflammation Value in Patients with Chronic Rinosinusitis |
| title_short | Evaluation of The Pan-Immune-Inflammation Value in Patients with Chronic Rinosinusitis |
| title_sort | evaluation of the pan immune inflammation value in patients with chronic rinosinusitis |
| topic | nasal polyps sinusitis inflammation indices |
| url | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/8573754A67DC49469D5D011306774063 |
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