State of the Retina and Visual Functions before and after Pancreatic Transplantation (Clinical Case)
In this report, we reflected a clinical case of the course of the proliferative stage of diabetic retinopathy in a patient suffering from type 1 diabetes mellitus (DM) and end-stage diabetic nephropathy (DN) before and after simultaneous pancreas and kidney transplantation. As a result of successful...
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| Format: | Article |
| Language: | Russian |
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Ophthalmology Publishing Group
2023-01-01
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| Series: | Oftalʹmologiâ |
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| Online Access: | https://www.ophthalmojournal.com/opht/article/view/2005 |
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| author | E. V. Bulava I. V. Vorobyeva A. V. Pinchuk |
| author_facet | E. V. Bulava I. V. Vorobyeva A. V. Pinchuk |
| author_sort | E. V. Bulava |
| collection | DOAJ |
| description | In this report, we reflected a clinical case of the course of the proliferative stage of diabetic retinopathy in a patient suffering from type 1 diabetes mellitus (DM) and end-stage diabetic nephropathy (DN) before and after simultaneous pancreas and kidney transplantation. As a result of successful surgical treatment of DM and DN was achieved physiological normoglycemia (change in fasting blood glucose from 11 to 5.1 mmol/l, glycated hemoglobin level from 9.2 to 5.7 %) and relief of uremic syndrome (change in serum creatinine from 632 to 77,5 µmol/l, urea from 13 to 6 mmol/l, glomerular filtration rate from 7.1 to 83.5 ml/min/1.73 m2). By the end of the first year of the post-transplantation period according to ophthalmoscopy data on the fundus no regression of the initial and addition of new diabetic changes was recorded and according to special instrumental methods of research was recorded a partial improvement hemoperfusion in superficial (an increase in the whole perfusion density: OD — from 24 to 35 %; OS — from 23 to 33 %) and deep (increase in the whole perfusion density: OD — from 5 to 13 %; OS — from 4 to 6 %) capillary plexus, a decrease in the central thickness of the retina (OD — from 269 to 257 µm; OS — from 271 to 253 µm) with resorption of intraretinal fluid in the right eye, improvement of the visual acuity (OD — from 0.5 to 0.7; OS — 0.6 to 0.7) and light sensitivity (macula light sensitivity threshold: OD — from 16.5 to 21.8 dB; OS — from 22.1 to 25.4 dB) of both eyes. |
| format | Article |
| id | doaj-art-5d55592dd469470a91e4b9c227aab286 |
| institution | Kabale University |
| issn | 1816-5095 2500-0845 |
| language | Russian |
| publishDate | 2023-01-01 |
| publisher | Ophthalmology Publishing Group |
| record_format | Article |
| series | Oftalʹmologiâ |
| spelling | doaj-art-5d55592dd469470a91e4b9c227aab2862025-08-20T04:00:25ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452023-01-0119491792210.18008/1816-5095-2022-4-917-922990State of the Retina and Visual Functions before and after Pancreatic Transplantation (Clinical Case)E. V. Bulava0I. V. Vorobyeva1A. V. Pinchuk2Russian Medical Academy of Continuous Professional EducationRussian Medical Academy of Continuous Professional Education; RUDN UniversityN.V. Sklifosovskiy Research Institute for Emergency Medical Aid; A.I. Evdokimov Moscow University of Medicine & Dentistry; Research Institute of Public Health Organization and Medical ManagementIn this report, we reflected a clinical case of the course of the proliferative stage of diabetic retinopathy in a patient suffering from type 1 diabetes mellitus (DM) and end-stage diabetic nephropathy (DN) before and after simultaneous pancreas and kidney transplantation. As a result of successful surgical treatment of DM and DN was achieved physiological normoglycemia (change in fasting blood glucose from 11 to 5.1 mmol/l, glycated hemoglobin level from 9.2 to 5.7 %) and relief of uremic syndrome (change in serum creatinine from 632 to 77,5 µmol/l, urea from 13 to 6 mmol/l, glomerular filtration rate from 7.1 to 83.5 ml/min/1.73 m2). By the end of the first year of the post-transplantation period according to ophthalmoscopy data on the fundus no regression of the initial and addition of new diabetic changes was recorded and according to special instrumental methods of research was recorded a partial improvement hemoperfusion in superficial (an increase in the whole perfusion density: OD — from 24 to 35 %; OS — from 23 to 33 %) and deep (increase in the whole perfusion density: OD — from 5 to 13 %; OS — from 4 to 6 %) capillary plexus, a decrease in the central thickness of the retina (OD — from 269 to 257 µm; OS — from 271 to 253 µm) with resorption of intraretinal fluid in the right eye, improvement of the visual acuity (OD — from 0.5 to 0.7; OS — 0.6 to 0.7) and light sensitivity (macula light sensitivity threshold: OD — from 16.5 to 21.8 dB; OS — from 22.1 to 25.4 dB) of both eyes.https://www.ophthalmojournal.com/opht/article/view/2005type 1 diabetes mellitusdiabetic retinopathydiabetic nephropathysimultaneous pancreas and kidney transplantationoptical coherence tomography angiographymicroperimetry |
| spellingShingle | E. V. Bulava I. V. Vorobyeva A. V. Pinchuk State of the Retina and Visual Functions before and after Pancreatic Transplantation (Clinical Case) Oftalʹmologiâ type 1 diabetes mellitus diabetic retinopathy diabetic nephropathy simultaneous pancreas and kidney transplantation optical coherence tomography angiography microperimetry |
| title | State of the Retina and Visual Functions before and after Pancreatic Transplantation (Clinical Case) |
| title_full | State of the Retina and Visual Functions before and after Pancreatic Transplantation (Clinical Case) |
| title_fullStr | State of the Retina and Visual Functions before and after Pancreatic Transplantation (Clinical Case) |
| title_full_unstemmed | State of the Retina and Visual Functions before and after Pancreatic Transplantation (Clinical Case) |
| title_short | State of the Retina and Visual Functions before and after Pancreatic Transplantation (Clinical Case) |
| title_sort | state of the retina and visual functions before and after pancreatic transplantation clinical case |
| topic | type 1 diabetes mellitus diabetic retinopathy diabetic nephropathy simultaneous pancreas and kidney transplantation optical coherence tomography angiography microperimetry |
| url | https://www.ophthalmojournal.com/opht/article/view/2005 |
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