Identification of CLEC10A as a human lectin for pancreatic ductal adenocarcinoma

Identification of CLEC10A as a human lectin for pancreatic ductal adenocarcinoma

Abstract The mechanism by which glycans in pancreatic ductal adenocarcinoma (PDAC) interact with human endogenous lectins in the tumor microenvironment remains largely unknown. This study aimed to identify endogenous lectins that recognize and bind to pancreatic ductal adenocarcinomas. The reactivit...

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Main Authors: Shuntaro Tsukamoto, Hiroaki Tateno, Osamu Shimomura, Kana Yamamoto, Sayoko Saito, Jinko Murakami, Hiromitsu Nakahashi, Yoshihiro Miyazaki, Tsuyoshi Enomoto, Tatsuya Oda
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
CLEC10A protein
Endogenous lectin
Pancreatic cancer
Tumor microenvironment
Online Access:https://doi.org/10.1038/s41598-025-02404-1
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