ENaC is a host susceptibility factor to bacterial infections in cystic fibrosis context

ENaC is a host susceptibility factor to bacterial infections in cystic fibrosis context

Abstract Cystic fibrosis (CF) is a genetic disease caused by dysfunction in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) chloride channel. Patients with CF are hypersusceptible to Mycobacterium abscessus infection, a fast-growing mycobacterium and harmful opportunistic pathogen. Al...

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Bibliographic Details
Main Authors: Hamadoun Touré, Nicolas Durand, Mickael Orgeur, Lee Ann Galindo, Fabienne Girard-Misguich, Isabelle Guénal, Jean-Louis Herrmann, Sébastien Szuplewski
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07877-4
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