EGFR polymorphisms drive lung cancer risk and survival disparities: a genotype-expression-outcome cohort study

EGFR polymorphisms drive lung cancer risk and survival disparities: a genotype-expression-outcome cohort study

PurposeTo investigate the correlation between single-nucleotide polymorphisms (SNPs) of the Epidermal growth factor receptor (EGFR) gene and its protein expression with susceptibility and survival prognosis of lung cancer (LC) patients.MethodsUsing SNP-scan high-throughput technology, the EGFR gene’...

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Bibliographic Details
Main Authors: Chao Zuo, Ziqiang Wang, Yi Liu, Jing Cheng, Dongli Yang, Yu Wang, Yongchao Qiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Genetics
Subjects:
EGFR
polymorphism
lung cancer
susceptibility
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1591539/full
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