Fat-cartilage axis: the regulation of IL-6/Osteopontin signaling in osteoarthritis of mice
Abstract The infrapatellar fat pad (IPFP) acts as a bioactive reservoir, secreting proinflammatory cytokines that orchestrate both local and systemic inflammatory cascades. Despite its emerging role in knee osteoarthritis (OA) pathophysiology, the molecular and cellular mechanisms driving IPFP-media...
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| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-07-01
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| Series: | Cell Death Discovery |
| Online Access: | https://doi.org/10.1038/s41420-025-02622-6 |
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