Haloperidol drug repurposing unveils ferroptosis involvement in breast cancer cells

Haloperidol drug repurposing unveils ferroptosis involvement in breast cancer cells

Abstract Breast cancer (BC) remains a leading cause of cancer-related mortality among women, with therapeutic resistance posing significant challenges. This study explores haloperidol (Halo), a clinically approved antipsychotic drug, for its potential antitumoral effects and ability to induce ferrop...

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Bibliographic Details
Main Authors: Valeria Consoli, Valeria Sorrenti, Salvatore Saccone, Concetta Federico, Francesca Bruno, Domenico Andrea Cristaldi, Valeria Pittalà, Sebastiano Intagliata, Luca Vanella
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Haloperidol
Cancer
Ferroptosis
Oxidative stress
Heme oxygenase
Online Access:https://doi.org/10.1038/s41598-025-12645-9
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