Poly (butylene adipate-co-terephthalate) (PBAT) in biomedical applications: a comprehensive review of material properties, fabrication methods, and biofunctional potential
Synthetic aliphatic and aromatic polyesters are extensively employed in biomedical contexts. In recent times, copolyesters have garnered increased scholarly interest for their capacity to amalgamate the benefits of both aromatic and aliphatic constituents. Poly (butylene adipate-co-terephthalate) (P...
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| Format: | Article |
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IOP Publishing
2025-01-01
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| Series: | Materials Research Express |
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| Online Access: | https://doi.org/10.1088/2053-1591/ade498 |
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| author | Animita Das Chethan K N Sampath Suranjan Salins Raviraj Shetty Sawan Shetty |
| author_facet | Animita Das Chethan K N Sampath Suranjan Salins Raviraj Shetty Sawan Shetty |
| author_sort | Animita Das |
| collection | DOAJ |
| description | Synthetic aliphatic and aromatic polyesters are extensively employed in biomedical contexts. In recent times, copolyesters have garnered increased scholarly interest for their capacity to amalgamate the benefits of both aromatic and aliphatic constituents. Poly (butylene adipate-co-terephthalate) (PBAT), commonly used in the agriculture and packaging industry, has recently gained attention for various biomedical applications owing to its biocompatibility, reduced crystallinity, attractive biodegradability, and mechanical properties. Integrating functional nanoparticles and polymers within PBAT further augments its mechanical integrity, bioactivity, and overall utility in applications. Despite its advantages, PBAT remains quite overlooked when stacked against other biodegradable polymers, especially concerning its biocompatibility and bioactivity. Various fabrication approaches, such as electrospinning, solvent casting, and 3D printing, have been used to develop PBAT-based structures. This review seeks to fill this lacuna by examining PBAT’s material characteristics, fabrication methodologies, and their resultant effects on its mechanical, bioactive, and biocompatible properties. It also underscores the biomedical applications of PBAT-based composites and blends. By synthesizing contemporary research, this article aspires to furnish significant insights for the development of efficient PBAT-based solutions within the biomedical arena, thereby laying a foundation for forthcoming advancements. |
| format | Article |
| id | doaj-art-5d4a196dcfde40d4bce2167c32294b31 |
| institution | OA Journals |
| issn | 2053-1591 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | IOP Publishing |
| record_format | Article |
| series | Materials Research Express |
| spelling | doaj-art-5d4a196dcfde40d4bce2167c32294b312025-08-20T02:21:34ZengIOP PublishingMaterials Research Express2053-15912025-01-0112606200210.1088/2053-1591/ade498Poly (butylene adipate-co-terephthalate) (PBAT) in biomedical applications: a comprehensive review of material properties, fabrication methods, and biofunctional potentialAnimita Das0https://orcid.org/0009-0008-5169-2517Chethan K N1https://orcid.org/0000-0002-9399-685XSampath Suranjan Salins2Raviraj Shetty3https://orcid.org/0000-0002-8256-5966Sawan Shetty4https://orcid.org/0000-0001-6384-1489Department of Mechanical and Industrial Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education , Manipal 576104, Karnataka, IndiaDepartment of Aeronautical & Automobile Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education , Manipal-576104, Karnataka, IndiaManipal Academy of Higher Education Dubai Campus, PO 345050, Dubai International Academic City, United Arab EmiratesDepartment of Mechanical and Industrial Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education , Manipal 576104, Karnataka, IndiaDepartment of Mechanical and Industrial Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education , Manipal 576104, Karnataka, IndiaSynthetic aliphatic and aromatic polyesters are extensively employed in biomedical contexts. In recent times, copolyesters have garnered increased scholarly interest for their capacity to amalgamate the benefits of both aromatic and aliphatic constituents. Poly (butylene adipate-co-terephthalate) (PBAT), commonly used in the agriculture and packaging industry, has recently gained attention for various biomedical applications owing to its biocompatibility, reduced crystallinity, attractive biodegradability, and mechanical properties. Integrating functional nanoparticles and polymers within PBAT further augments its mechanical integrity, bioactivity, and overall utility in applications. Despite its advantages, PBAT remains quite overlooked when stacked against other biodegradable polymers, especially concerning its biocompatibility and bioactivity. Various fabrication approaches, such as electrospinning, solvent casting, and 3D printing, have been used to develop PBAT-based structures. This review seeks to fill this lacuna by examining PBAT’s material characteristics, fabrication methodologies, and their resultant effects on its mechanical, bioactive, and biocompatible properties. It also underscores the biomedical applications of PBAT-based composites and blends. By synthesizing contemporary research, this article aspires to furnish significant insights for the development of efficient PBAT-based solutions within the biomedical arena, thereby laying a foundation for forthcoming advancements.https://doi.org/10.1088/2053-1591/ade498poly (butylene adipate-co-terephthalate)biocompatibilityelectrospinningsolvent casting3D printing |
| spellingShingle | Animita Das Chethan K N Sampath Suranjan Salins Raviraj Shetty Sawan Shetty Poly (butylene adipate-co-terephthalate) (PBAT) in biomedical applications: a comprehensive review of material properties, fabrication methods, and biofunctional potential Materials Research Express poly (butylene adipate-co-terephthalate) biocompatibility electrospinning solvent casting 3D printing |
| title | Poly (butylene adipate-co-terephthalate) (PBAT) in biomedical applications: a comprehensive review of material properties, fabrication methods, and biofunctional potential |
| title_full | Poly (butylene adipate-co-terephthalate) (PBAT) in biomedical applications: a comprehensive review of material properties, fabrication methods, and biofunctional potential |
| title_fullStr | Poly (butylene adipate-co-terephthalate) (PBAT) in biomedical applications: a comprehensive review of material properties, fabrication methods, and biofunctional potential |
| title_full_unstemmed | Poly (butylene adipate-co-terephthalate) (PBAT) in biomedical applications: a comprehensive review of material properties, fabrication methods, and biofunctional potential |
| title_short | Poly (butylene adipate-co-terephthalate) (PBAT) in biomedical applications: a comprehensive review of material properties, fabrication methods, and biofunctional potential |
| title_sort | poly butylene adipate co terephthalate pbat in biomedical applications a comprehensive review of material properties fabrication methods and biofunctional potential |
| topic | poly (butylene adipate-co-terephthalate) biocompatibility electrospinning solvent casting 3D printing |
| url | https://doi.org/10.1088/2053-1591/ade498 |
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