The difficult laparoscopic cholecystectomy: a narrative review

Abstract Background/purpose Laparoscopic cholecystectomy is one of the most commonly performed general surgical procedures. Difficult laparoscopic cholecystectomy is associated with increased operative time, hospital stay, complication rates, open conversion, treatment costs, and mortality. This stu...

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Main Authors: Hamdy S. Abdallah, Mohamad H. Sedky, Zyad H. Sedky
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Surgery
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Online Access:https://doi.org/10.1186/s12893-025-02847-3
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author Hamdy S. Abdallah
Mohamad H. Sedky
Zyad H. Sedky
author_facet Hamdy S. Abdallah
Mohamad H. Sedky
Zyad H. Sedky
author_sort Hamdy S. Abdallah
collection DOAJ
description Abstract Background/purpose Laparoscopic cholecystectomy is one of the most commonly performed general surgical procedures. Difficult laparoscopic cholecystectomy is associated with increased operative time, hospital stay, complication rates, open conversion, treatment costs, and mortality. This study aimed to provide a comprehensive literature review on difficult laparoscopic cholecystectomy. Methods A literature search was conducted for articles published in English up to June 2024 using common databases including PubMed/MIDLINE, Web of Science, Google Scholar, and ScienceDirect. Keywords included “safe laparoscopic cholecystectomy”, “difficult laparoscopic cholecystectomy”, “acute cholecystitis”, “prevention of bile duct injuries”, “intraoperative cholangiography,” “bailout procedure,” and “subtotal cholecystectomy”. Only clinical trials, systematic reviews/meta-analyses, and review articles were included. Studies involving children, robotic cholecystectomy, single incision laparoscopic cholecystectomy, open cholecystectomy, and cholecystectomy for indications other than gallstone disease were excluded. Results/discussion Emergency laparoscopic cholecystectomy for acute cholecystitis is ideally performed within 72 h of symptom onset, with a maximum window of 7–10 days. Intraoperative cholangiography can help clarify unclear biliary anatomy and detect bile duct injuries. In the “impossible gallbladder”, laparoscopic cholecystostomy or gallbladder aspiration may be considered. When dissection of Calot’s triangle is deemed hazardous or impossible, the fundus-first approach allows for completion of the procedure with either total cholecystectomy or subtotal cholecystectomy. Subtotal cholecystectomy is effective in preventing bile duct injuries, can be performed laparoscopically, and is currently the best available bailout approach for difficult laparoscopic cholecystectomy. Conclusion Difficult laparoscopic cholecystectomy is a common clinical scenario that requires a judicious approach by experienced surgeons in appropriate settings. When difficult laparoscopic cholecystectomy is encountered, various bailout strategies are available. Currently, subtotal cholecystectomy is likely the most effective bailout approach.
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spelling doaj-art-5d3fcf161ed04e97ade3994cc83bcf452025-08-20T02:11:59ZengBMCBMC Surgery1471-24822025-04-0125111710.1186/s12893-025-02847-3The difficult laparoscopic cholecystectomy: a narrative reviewHamdy S. Abdallah0Mohamad H. Sedky1Zyad H. Sedky2Department of General Surgery, Tanta University Teaching HospitalKasr-Alainy Faculty of Medicine, Cairo UniversityKasr-Alainy Faculty of Medicine, Cairo UniversityAbstract Background/purpose Laparoscopic cholecystectomy is one of the most commonly performed general surgical procedures. Difficult laparoscopic cholecystectomy is associated with increased operative time, hospital stay, complication rates, open conversion, treatment costs, and mortality. This study aimed to provide a comprehensive literature review on difficult laparoscopic cholecystectomy. Methods A literature search was conducted for articles published in English up to June 2024 using common databases including PubMed/MIDLINE, Web of Science, Google Scholar, and ScienceDirect. Keywords included “safe laparoscopic cholecystectomy”, “difficult laparoscopic cholecystectomy”, “acute cholecystitis”, “prevention of bile duct injuries”, “intraoperative cholangiography,” “bailout procedure,” and “subtotal cholecystectomy”. Only clinical trials, systematic reviews/meta-analyses, and review articles were included. Studies involving children, robotic cholecystectomy, single incision laparoscopic cholecystectomy, open cholecystectomy, and cholecystectomy for indications other than gallstone disease were excluded. Results/discussion Emergency laparoscopic cholecystectomy for acute cholecystitis is ideally performed within 72 h of symptom onset, with a maximum window of 7–10 days. Intraoperative cholangiography can help clarify unclear biliary anatomy and detect bile duct injuries. In the “impossible gallbladder”, laparoscopic cholecystostomy or gallbladder aspiration may be considered. When dissection of Calot’s triangle is deemed hazardous or impossible, the fundus-first approach allows for completion of the procedure with either total cholecystectomy or subtotal cholecystectomy. Subtotal cholecystectomy is effective in preventing bile duct injuries, can be performed laparoscopically, and is currently the best available bailout approach for difficult laparoscopic cholecystectomy. Conclusion Difficult laparoscopic cholecystectomy is a common clinical scenario that requires a judicious approach by experienced surgeons in appropriate settings. When difficult laparoscopic cholecystectomy is encountered, various bailout strategies are available. Currently, subtotal cholecystectomy is likely the most effective bailout approach.https://doi.org/10.1186/s12893-025-02847-3Safe laparoscopic cholecystectomyDifficult laparoscopic cholecystectomyAcute cholecystitisBile duct injuriesIntraoperative cholangiographyBailout procedure
spellingShingle Hamdy S. Abdallah
Mohamad H. Sedky
Zyad H. Sedky
The difficult laparoscopic cholecystectomy: a narrative review
BMC Surgery
Safe laparoscopic cholecystectomy
Difficult laparoscopic cholecystectomy
Acute cholecystitis
Bile duct injuries
Intraoperative cholangiography
Bailout procedure
title The difficult laparoscopic cholecystectomy: a narrative review
title_full The difficult laparoscopic cholecystectomy: a narrative review
title_fullStr The difficult laparoscopic cholecystectomy: a narrative review
title_full_unstemmed The difficult laparoscopic cholecystectomy: a narrative review
title_short The difficult laparoscopic cholecystectomy: a narrative review
title_sort difficult laparoscopic cholecystectomy a narrative review
topic Safe laparoscopic cholecystectomy
Difficult laparoscopic cholecystectomy
Acute cholecystitis
Bile duct injuries
Intraoperative cholangiography
Bailout procedure
url https://doi.org/10.1186/s12893-025-02847-3
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