A simple approach for classifying new mutations as somatic or germinal in DNA samples lacking paired tissue
When studying mutations in DNA samples, determining whether novel sequence changes are somatic mutations or germline polymorphisms can be difficult. Here we describe a novel and very simple approach for identification of somatic mutations and loss of heterozygosity (LoH) events in DNA samples where...
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| Main Authors: | Ignacio Erquiaga, Cristina Hurtado, Paula Aranaz, Francisco J. Novo, José L. Vizmanos |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2014-06-01
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| Series: | BioTechniques |
| Subjects: | |
| Online Access: | https://www.future-science.com/doi/10.2144/000114180 |
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